ArticleJournal of child neurology2013
Spectrum and prevalence of vasculopathy in pediatric neurofibromatosis type 1.
Article in Journal of child neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk of Cerebrovascular Events Among Childhood and Adolescent Patients Receiving Cranial Radiation Therapy: A PENTEC Normal Tissue Outcomes Comprehensive Review.International journal of radiation oncology, biology, physics · 2024Pooled it
- Association between neurofibromatosis type 1 and cerebrovascular diseases in children: A systematic review.PloS one · 2021Pooled it
- Delayed diagnosis of neurofibromatosis type I with an index presentation of haemothorax.Journal of surgical case reports · 2026Article
- Aorto-Renal Dysplasia in Childhood: The Overlap of Neurofibromatosis Type 1 and Pediatric Renovascular Hypertension.Current hypertension reports · 2026Review
- Magnetic Resonance Imaging of Central Nervous System Manifestations of Type 1 Neurofibromatosis: Pictorial Review and Retrospective Study of Their Frequency in a Cohort of Patients.Journal of clinical medicine · 2024Article
- Retinal Ischemia as a Presenting Ocular Sign of Neurofibromatosis Type 2.Case reports in ophthalmological medicine · 2024Article
- Review
- Neurofibromatosis Type 1: Pediatric Aspects and Review of Genotype-Phenotype Correlations.Cancers · 2023Review
- ERN GENTURIS tumour surveillance guidelines for individuals with neurofibromatosis type 1.EClinicalMedicine · 2023Review
- Case report: Revascularization failure in NF1-related moyamoya syndrome after selumetinib: A possible pathophysiological correlation?Frontiers in pediatrics · 2023Article
- [Neurofibromatosis type 1 : From diagnosis to follow-up].Radiologie (Heidelberg, Germany) · 2022Review
- Molecular genetic evaluation of pediatric renovascular hypertension due to renal artery stenosis and abdominal aortic coarctation in neurofibromatosis type 1.Human molecular genetics · 2022Article
- Diagnosis and Management of Genetic Causes of Middle Aortic Syndrome in Children: A Comprehensive Literature Review.Therapeutics and clinical risk management · 2022Review
- Renal manifestations in children with neurofibromatosis type 1.European journal of pediatrics · 2021Article
- Microcephalic osteodysplastic primordial dwarfism type II is associated with global vascular disease.Orphanet journal of rare diseases · 2021Article
- Non-Oncological Neuroradiological Manifestations in NF1 and Their Clinical Implications.Cancers · 2021Review
- Hypertension and childhood stroke.Pediatric nephrology (Berlin, Germany) · 2021Review
- Hypertension in Children and Adolescents with Turner Syndrome (TS), Neurofibromatosis 1 (NF1), and Williams Syndrome (WS).Current hypertension reports · 2021Review
- Ask-Upmark kidney in a girl with neurofibromatosis type 1.CEN case reports · 2020Article
- [Lethal Hemomediastinum due to Spontaneous Rupture of an Aberrant Bronchial Artery in a Patient with Neurofibromatosis Type 1: Successful Treatment with Embolization].Taehan Yongsang Uihakhoe chi · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
To describe the spectrum and associated clinical features of peripheral and cerebral vasculopathy in pediatric patients with neurofibromatosis type 1, children seen at a single center from 2000 to 2010 with appropriate imaging studies were identified. Scans were assessed for vascular disease by 2 pediatric neuroradiologists. Of 181 children, 80 had pertinent imaging studies: 77 had brain imaging, 6 had peripheral imaging, and 3 had both. Vasculopathy was identified in 14/80 children (18%, minimum prevalence of 14/181; 8%). Of those with vascular abnormalities, 2/14 had peripheral vasculopathy (1% minimum prevalence) and 12/14 had cerebrovascular abnormalities (7% minimum prevalence). No associations were found between vasculopathy and common clinical features of neurofibromatosis type 1, including optic pathway glioma, plexiform neurofibroma, skeletal abnormalities, attention-deficit hyperactivity disorder (ADHD), or suspected learning disability. Both peripheral and cerebral vasculopathy are important complications of pediatric neurofibromatosis type 1 and should be considered in the management of this complex disease.
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Registered trials
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