ArticlePediatric nephrology (Berlin, Germany)2012
Renal function and systolic blood pressure in very-low-birth-weight infants 1-3 years of age.
Article in Pediatric nephrology (Berlin, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Follow-up of a randomized trial optimizing neonatal nutrition in preterm very low birthweight infants: growth, serum adipokines, renal function and blood pressure.Journal of perinatology : official journal of the California Perinatal Association · 2024Trial
- Optimizing individual nutrition in preterm very low birth weight infants: double-blinded randomized controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2020Trial
- Relationship between serum lipids/adipokines and obesity/hypertension in very-preterm infants during early childhood and preadolescence.Pediatric research · 2026Article
- Development of a Family-Centered Communication Tool for Kidney Health in Premature Infants: Qualitative Focus Group Study Using Human-Centered Design Methodology.Journal of participatory medicine · 2023Article
- Quality improvement project designed to reduce disproportionate growth in extremely low gestational age neonates: cognitive neurodevelopmental outcome at 18-41 months.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Association of age of initiation and type of complementary foods with body mass index and weight-for-length at 12 months of age in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2020Observational
- Prevalence of hyperfiltration among US youth/young adults with overweight and obesity: A population-based association study.Obesity science & practice · 2019Article
- Adjustable feedings plus accurate serial length measurements decrease discharge weight-length disproportion in very preterm infants: quality improvement project.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- Effects of Prenatal Growth Status on Subsequent Childhood Renal Function Related to High Blood Pressure.Journal of Korean medical science · 2019Article
- Blood Pressure Trajectories from Childhood to Adolescence in Pediatric Hypertension.Korean circulation journal · 2019Review
- The Joint Association of Small for Gestational Age and Nighttime Sleep with Blood Pressure in Childhood.Scientific reports · 2018Article
- Prematurity and future kidney health: the growing risk of chronic kidney disease.Current opinion in pediatrics · 2018Review
- Preterm birth and ventilation decrease surface density of glomerular capillaries in lambs, regardless of postnatal respiratory support mode.Pediatric research · 2017Article
- Complications during pregnancy and fetal development: implications for the occurrence of chronic kidney disease.Expert review of cardiovascular therapy · 2017Review
- Article
- Making a diagnosis of hypertension and defining treatment threshold in very low birth weight infants' need revision?Journal of renal injury prevention · 2016Article
- Increased urinary angiotensinogen is an effective marker of chronic renal impairment in very low birth weight children.Clinical and experimental nephrology · 2014Observational
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm very-low-birth-weight (PT-VLBW) infants are at risk of an elevated systolic blood pressure (SBP) in infancy and adulthood; however, the pathogenesis remains unclear. Altered renal development or function may be associated with increased SBP, but their contribution in PT-VLBW is unknown.
methodsWe determined renal function and its relationship to SBP in three groups of PT-VLBW at 1, 2, and 3 years of age, using serum cystatin-C to calculate the estimated glomerular filtration rate (eGFR).
resultsCystatin-C levels decreased from 0.84 ± 0.2 (SD) within the 1-year group to 0.70 ± 0.1 mg/l (±SD; P < 0.001) at 3 years and were unrelated to gender, fetal growth, and neonatal indomethacin exposure. eGFR rose from 121 ± 59 in the 1-year group to 138 ± 21 ml/min · 1.73 m(2) (P < 0.001) at 3 years. At 1 year, cystatin-C levels decreased with increasing SBP (P < 0.007), and infants with SBP ≥ 90 th% had lower cystatin-C and higher eGFR (P < 0.05). At 3 years, infants with lower birth weight (P < 0.03) and gestational age (P = 0.06) had reduced eGFR.
conclusionsPreterm very-low-birth-weight infants demonstrate increasing renal function with advancing age. An elevated SBP and eGFR at 1 year suggests dysfunctional renal autoregulation and hyperfiltration, which may alter subsequent renal function and contribute to the lower eGFR seen at 3 years in infants with the lowest birth weight and gestational age.
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