Evidence map›Paper›PMID 22832540›Full record

Trial reportPsychotherapy and psychosomatics2012

Mindfulness-based cognitive therapy improves polysomnographic and subjective sleep profiles in antidepressant users with sleep complaints.

Willoughby B Britton, Patricia L Haynes, Keith W Fridel, Richard R Bootzin

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychotherapy and psychosomatics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03949296 (A Randomized, Placebo-Controlled Study of Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis), which is not on this map. Cited by 37 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 5 pooled it
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03949296 nacompletednot on this mapstarted 2017, after this paper: background citation

A Randomized, Placebo-Controlled Study of Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis

TypeinterventionalSponsorGriffin HospitalRan2017 to 2019Enrolled49ConditionsInsomnia Chronic, Multiple SclerosisArmsMindfulness Intervention, Sleep Hygiene
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 5 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Systematic Review for the Medical Applications of Meditation in Randomized Controlled Trials.International journal of environmental research and public health · 2022
    Pooled it
  3. Psychological therapies for treatment-resistant depression in adults.The Cochrane database of systematic reviews · 2018
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Willoughby B BrittonDepartment of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI 02906, USA. willoughby_britton @ brown.edu
Patricia L Haynes
Keith W Fridel
Richard R Bootzin
Brown University · USSouthern Arizona VA Health Care System · US

Funding

Arizona Complementary and Alternative Medicine Research Training ProgramT32AT001287 · NCCIH · UNIVERSITY OF ARIZONA · PI BELL, IRIS ROBERTA · 2002 to 2011
$3.2M
Training in Treatment ResearchT32MH067553 · NIMH · BROWN UNIVERSITY · PI MILLER, IVAN W. · 2003 to 2012
$1.6M
Dismantling Mindfulness: Contributions of Attention vs. AcceptanceK23AT006328 · NCCIH · BROWN UNIVERSITY · PI BRITTON, WILLOUGHBY · 2011 to 2015
$667k
NCCIH NIH HHS K23 AT006328NCCIH NIH HHS K23-AT006328-01A1NCCIH NIH HHS T32 AT001287NCCIH NIH HHS T32-AT001287NIMH NIH HHS MH067553-05NIMH NIH HHS T32 MH067553
6 · The paper itself

Abstract

backgroundMany antidepressant medications (ADM) are associated with disruptions in sleep continuity that can compromise medication adherence and impede successful treatment. The present study investigated whether mindfulness meditation (MM) training could improve self-reported and objectively measured polysomnographic (PSG) sleep profiles in depressed individuals who had achieved at least partial remission with ADM, but still had residual sleep complaints.

methodsTwenty-three ADM users with sleep complaints were randomized into an 8-week Mindfulness-Based Cognitive Therapy (MBCT) course or a waitlist control condition. Pre-post measurements included PSG sleep studies and subjectively reported sleep, residual depression symptoms.

resultsCompared to controls, the MBCT participants improved on both PSG and subjective measures of sleep. They showed a pattern of decreased wake time and increased sleep efficiency. Sleep depth, as measured by stage 1 and slow-wave sleep, did not change as a result of mindfulness training.

conclusionsMM is associated with increases in both objectively and subjectively measured sleep continuity in ADM users. MM training may serve as more desirable and cost-effective alternative to discontinuation or supplementation with hypnotics, and may contribute to a more sustainable recovery from depression.

Indexed as

MeditationAdultAnalysis of VarianceAntidepressive AgentsCognitive Behavioral TherapyDepressive DisorderFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePolysomnographyPsychiatric Status Rating ScalesRecurrenceSleep Initiation and Maintenance DisordersAntidepressive Agents

Identifiers

PMID22832540
PMCPMC3495555
OpenAlexW2081594108

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.