ReviewBrain and language2013
Thalamic mechanisms in language: a reconsideration based on recent findings and concepts.
Review in Brain and language, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03668132 (The Language Functional Reorganization Following Subcortical Cerebral Infarction), which is not on this map. Cited by 72 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Language Functional Reorganization Following Subcortical Cerebral Infarction: A Longitudinal fMRI Study
Who cites it
72 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Contributions of the left and right thalami to language: A meta-analytic approach.Brain structure & function · 2024Pooled it
- Examination of common and unique brain regions for atypical reading and math: a meta-analysis.Cerebral cortex (New York, N.Y. : 1991) · 2023Pooled it
- Diagnosing and managing post-stroke aphasia.Expert review of neurotherapeutics · 2021Trial
- Thalamic aphasia as an uncommon manifestation of thalamic stroke due to artery of Percheron occlusion: Case report with literature review.Radiology case reports · 2026Article
- Comparative analysis of Foxp2 expression in the thalamus of mice, rats, and macaques: implications for the evolution of language circuits.Brain structure & function · 2026Article
- Medial Pulvinar Nucleus as a Causal Hub for Heteromodal Naming.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Object Naming After Thalamic Damage: Evidence From a Large-Scale, Chronic-Phase Study of Left Hemisphere Stroke Survivors.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Category-Specific Semantic Impairment After Left Anterior Thalamic Infarction: A Case Report.Cureus · 2026Article
- Distributed cortico-subcortical networks enable robust speech state detection from sparse intracranial recordings.Frontiers in neuroscience · 2026Article
- Pulvinar subdivisions and connectivity patterns across primate species: a comparative perspective.Frontiers in neuroanatomy · 2026Review
- Article
- Executive Functions Training Improves Language Abilities in Aphasia Rehabilitation: A Systematic Review.Journal of personalized medicine · 2025Review
- Neural adaptations in short-term learning of sign language revealed by fMRI and DTI.Scientific reports · 2025Article
- Neural correlates of auditory comprehension and integration of sanskrit verse: a functional MRI study.Brain structure & function · 2025Article
- Structure-function interrelationships and associated neurotransmitter profiles in drug-naïve benign childhood epilepsy with central-temporal spikes patients.European radiology · 2025Article
- A reappraisal of the role of the mammillothalamic tract in memory deficits following stroke in the thalamus.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The Connectional Diaschisis and Normalization of Cortical Language Network Dynamics After Basal Ganglia and Thalamus Stroke.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Frequency-specific cortico-subcortical interaction in continuous speaking and listening.eLife · 2024Article
- Multimodal study of multilevel pulvino-temporal connections: a new piece in the puzzle of lexical retrieval networks.Brain : a journal of neurology · 2024Article
- An inclusive multivariate approach to neural localization of language components.Brain structure & function · 2024Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Recent literature on thalamic aphasia and thalamic activity during neuroimaging is selectively reviewed followed by a consideration of recent anatomic and physiological findings regarding thalamic structure and functions. It is concluded that four related corticothalamic and/or thalamocortical mechanisms impact language processing: (1) selective engagement of task-relevant cortical areas in a heightened state of responsiveness in part through the nucleus reticularis (NR), (2) passing information from one cortical area to another through corticothalamo-cortical mechanisms, (3) sharpening the focus on task-relevant information through corticothalamo-cortical feedback mechanisms, and (4) selection of one language unit over another in the expression of a concept, accomplished in concert with basal ganglia loops. The relationship and interaction of these mechanisms is discussed and integrated with thalamic aphasia and neuroimaging data into a theory of thalamic functions in language.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.