ReviewMicrobial cell factories2012
Microalgal biofactories: a promising approach towards sustainable omega-3 fatty acid production.
Review in Microbial cell factories, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
142 citing papers in PubMed, 610 citations in OpenAlex.
- Re-esterified DHA improves ventilatory threshold 2 in competitive amateur cyclists.Journal of the International Society of Sports Nutrition · 2020Trial
- Perspectives on dietary polyunsaturated fatty acid supplementation for enhanced immunity in healthy and ill dogs: a narrative review.Veterinary and animal science · 2026Review
- Food-Derived Omega-3 Fatty Acids and Cognitive Aging: Integrating Nutritional Neuroscience and Geroscience.Nutrients · 2026Review
- Vitamin BMicrobial ecology · 2026Article
- Predictive Algal Systems Biology: Integrating Omics, Genome-Scale Metabolic Models, and Machine Learning.Bioengineering (Basel, Switzerland) · 2026Review
- Techno-economic analysis of bioactive-rich oil production from Nannochloropsis oculata.Scientific reports · 2026Article
- Influence of harvesting method on biomass yield and antimicrobial activity of Isochrysis galbana and Phaeodactylum tricornutum extracts.Biotechnology letters · 2026Article
- Supplementing the diet of Nile tilapia (Oreochromis niloticus) with microalgae Nannochloropsis oculata and Phaeodactylum tricornutum enhanced immune function, lipid profile, and resistance to Edwardsiella tarda infection.Veterinary research communications · 2026Article
- Abiotic stress effects on polyunsaturated fatty acid biosynthesis in Chlorococcum oleofaciens and Leptolyngbya sp.Applied microbiology and biotechnology · 2026Article
- Review
- Partial Replacement of Soybean Protein (30%) withFoods (Basel, Switzerland) · 2026Article
- Enhanced Production of Bioactive Polyunsaturated Fatty Acids and Pigments inMarine drugs · 2026Article
- Incorporation of omega-3 polyunsaturated fatty acids into glycerolipids in microalgaApplied and environmental microbiology · 2025Article
- Microalgal diversity, nutritional profiles, and applications in poultry nutrition: A comprehensive review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- Building a cell-factory in Crithidia fasciculata: a bio-sustainable system to produce high-value polyunsaturated fatty acids.Microbial cell factories · 2025Article
- Application of Microorganisms for the Valorization of Side-Products of Rapeseed De-Oiling.Biomolecules · 2025Review
- Unleashing the power of microalgae: a pioneering path to sustainability and achieving the sustainable development goals.Environmental science and pollution research international · 2025Review
- Exploring the Complexities of Seafood: From Benefits to Contaminants.Foods (Basel, Switzerland) · 2025Review
- Mixtures of Algal Oil and Terrestrial Oils in Diets of Tiger Puffer (Animals : an open access journal from MDPI · 2025Article
- How Close Are We to the Production of Milk in Alternative Systems? The Fat Perspective.Foods (Basel, Switzerland) · 2025Review
82 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) provide significant health benefits and this has led to an increased consumption as dietary supplements. Omega-3 fatty acids EPA and DHA are found in animals, transgenic plants, fungi and many microorganisms but are typically extracted from fatty fish, putting additional pressures on global fish stocks. As primary producers, many marine microalgae are rich in EPA (C20:5) and DHA (C22:6) and present a promising source of omega-3 fatty acids. Several heterotrophic microalgae have been used as biofactories for omega-3 fatty acids commercially, but a strong interest in autotrophic microalgae has emerged in recent years as microalgae are being developed as biofuel crops. This paper provides an overview of microalgal biotechnology and production platforms for the development of omega-3 fatty acids EPA and DHA. It refers to implications in current biotechnological uses of microalgae as aquaculture feed and future biofuel crops and explores potential applications of metabolic engineering and selective breeding to accumulate large amounts of omega-3 fatty acids in autotrophic microalgae.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.