ReviewOxidative medicine and cellular longevity2012
Exercise in the metabolic syndrome.
Review in Oxidative medicine and cellular longevity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Physical Inactivity and Metabolic Syndrome in the United Arab Emirates: A Systematic Review and Meta-analysis of Parallel Epidemics.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Metabolic syndrome is associated with breast cancer mortality: A systematic review and meta-analysis.Journal of internal medicine · 2025Pooled it
- Evidence of Use of Whole-Body Vibration in Individuals with Metabolic Syndrome: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Effects of sprint interval training combined with remote ischaemic preconditioning on vascular function in young women with masked obesity.European journal of applied physiology · 2026Trial
- Trial
- Adiponectin in relation to exercise and physical performance in patients with type 2 diabetes and coronary artery disease.Adipocyte · 2021Trial
- Time course of improvement of metabolic parameters after a 12 week physical exercise programme in patients with type 2 diabetes: the influence of gender in a Nigerian population.BioMed research international · 2013Trial
- DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise.PloS one · 2013Trial
- Does Lifestyle Exercise After a Cardiac Event Improve Metabolic Syndrome Profile in Older Adults?The Journal of cardiovascular nursingTrial
- Nutrition-related biomarkers of metabolic disorders among immigrants in Athens, Greece: a cross- sectional study.Journal of diabetes and metabolic disorders · 2025Article
- Chemerin as a Driver of Cardiovascular Diseases: New Perspectives and Future Directions.Biomedicines · 2025Review
- Observational
- Article
- Dietary habits and salivary cortisol levels as an early predictor of metabolic syndrome in children: a case-control study.Przeglad gastroenterologiczny · 2025Article
- Association of sarcopenia and physical activity on the severity of metabolic dysfunction-associated steatotic liver disease among United States adults: NHANES 2017 - 2018.Frontiers in aging · 2025Article
- Assessing gastric cancer risk through longitudinal health check-up data: Insights from a national cohort study in South Korea.PloS one · 2025Article
- Article
- Time-Restricted Feeding Ameliorates Methionine-Choline Deficient Diet-Induced Steatohepatitis in Mice.International journal of molecular sciences · 2024Article
- Physical activity in metabolic syndrome.Frontiers in physiology · 2024Review
- Implementation of a Budo group therapy for psychiatric in- and outpatients: a feasibility study.Frontiers in psychiatry · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The metabolic syndrome is a clustering of obesity, diabetes, hyperlipidemia, and hypertension that is occurring in increasing frequency across the global population. Although there is some controversy about its diagnostic criteria, oxidative stress, which is defined as imbalance between the production and inactivation of reactive oxygen species, has a major pathophysiological role in all the components of this disease. Oxidative stress and consequent inflammation induce insulin resistance, which likely links the various components of this disease. We briefly review the role of oxidative stress as a major component of the metabolic syndrome and then discuss the impact of exercise on these pathophysiological pathways. Included in this paper is the effect of exercise in reducing fat-induced inflammation, blood pressure, and improving muscular metabolism.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.