ReviewPLoS genetics2012
Genomic data reveal a complex making of humans.
Review in PLoS genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Article
- Human demographic history has amplified the effects of background selection across the genome.PLoS genetics · 2018Article
- A diffusion based study of population dynamics: Prehistoric migrations into South Asia.PloS one · 2017Article
- Can the experimental evolution programme help us elucidate the genetic basis of adaptation in nature?Molecular ecology · 2016Review
- Early modern human dispersal from Africa: genomic evidence for multiple waves of migration.Investigative genetics · 2015Article
- The peopling of the African continent and the diaspora into the new world.Current opinion in genetics & development · 2014Review
- Toward a new history and geography of human genes informed by ancient DNA.Trends in genetics : TIG · 2014Review
- Spatial and temporal simulation of human evolution. Methods, frameworks and applications.Current genomics · 2014Article
- Population-specific common SNPs reflect demographic histories and highlight regions of genomic plasticity with functional relevance.BMC genomics · 2014Article
- The impact of whole-genome sequencing on the reconstruction of human population history.Nature reviews. Genetics · 2014Review
- Human genome variation and the concept of genotype networks.PloS one · 2014Article
- Article
- Analysis of Patterns of Gene Expression Variation within and between Ethnic Populations in Pediatric B-ALL.Cancer informatics · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last few years, two paradigms underlying human evolution have crumbled. Modern humans have not totally replaced previous hominins without any admixture, and the expected signatures of adaptations to new environments are surprisingly lacking at the genomic level. Here we review current evidence about archaic admixture and lack of strong selective sweeps in humans. We underline the need to properly model differential admixture in various populations to correctly reconstruct past demography. We also stress the importance of taking into account the spatial dimension of human evolution, which proceeded by a series of range expansions that could have promoted both the introgression of archaic genes and background selection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.