ReviewArchives of dermatological research2012
The role of androgen and androgen receptor in skin-related disorders.
Review in Archives of dermatological research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 202 citations in OpenAlex.
- Pooled it
- Is acne in adolescence associated with prostate cancer risk? Evidence from a meta-analysis.PloS one · 2018Pooled it
- Weekly treatment with SAMiRNA targeting the androgen receptor ameliorates androgenetic alopecia.Scientific reports · 2022Trial
- Efficacy and Safety of Topical Clascoterone Cream, 1%, for Treatment in Patients With Facial Acne: Two Phase 3 Randomized Clinical Trials.JAMA dermatology · 2020Trial
- Clascoterone in the Treatment of Acne Vulgaris: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- The brain-skin connection: A narrative review of neuroendocrine and immune pathways.JAAD international · 2026Article
- Double Challenges for Scalp Health: A Review of the Pathogenesis and Treatment Strategies of Coexistence of Seborrheic Dermatitis and Androgenetic Alopecia.Dermatology research and practice · 2026Review
- Sex Bias in Autoimmunity: New Findings and New Opportunities.JID innovations : skin science from molecules to population health · 2025Review
- Effect of Androgens on Human Fascia.Biology · 2025Article
- New insights into the phenomenon of remissions and relapses in autoimmune diseases and the puzzle of benign autoantibodies in healthy individuals.Frontiers in immunology · 2025Review
- Global burden of viral skin diseases from 1990 to 2021: a systematic analysis for the global burden of disease study 2021.Frontiers in public health · 2025Article
- Hair Growth Effect and the Mechanisms ofInternational journal of molecular sciences · 2024Article
- No genetic causal relationship between acne and prostate cancer through Mendelian randomization combined with meta-analysis.Frontiers in oncology · 2024Article
- Metformin: A Potential Treatment for Acne, Hidradenitis Suppurativa and Rosacea.Acta dermato-venereologica · 2023Review
- Cell Therapy for Androgenetic Alopecia: Elixir or Trick?Stem cell reviews and reports · 2023Review
- Photopneumatic Technology for the Treatment of Mild-to-moderate Acne Vulgaris-A Review and Expert Perspectives.The Journal of clinical and aesthetic dermatology · 2023Article
- Sirtuin 6 is a key contributor to gender differences in acute kidney injury.Cell death discovery · 2023Article
- Characterizing Dermatological Conditions in the Transgender Population: A Cross-Sectional Study.Transgender health · 2023Article
- Insulin and the sebaceous gland function.Frontiers in physiology · 2023Review
- Guava (Plants (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
Androgen and androgen receptor (AR) may play important roles in several skin-related diseases, such as androgenetic alopecia and acne vulgaris. Current treatments for these androgen/AR-involved diseases, which target the synthesis of androgens or prevent its binding to AR, can cause significant adverse side effects. Based on the recent studies using AR knockout mice, it has been suggested that AR and androgens play distinct roles in the skin pathogenesis, and AR seems to be a better target than androgens for the treatment of these skin diseases. Here, we review recent studies of androgen/AR roles in several skin-related disorders, including acne vulgaris, androgenetic alopecia and hirsutism, as well as cutaneous wound healing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.