Evidence map›Paper›PMID 22829053›Full record

ArticleInternational journal of biological macromolecules2012

Effects of silica nanoparticle supported ionic liquid as additive on thermal reversibility of human carbonic anhydrase II.

Azadeh Fallah-Bagheri, Ali Akbar Saboury, Leila Ma'mani, Mohammad Taghizadeh, Reza Khodarahmi, Samira Ranjbar, Mousa Bohlooli, Abbas Shafiee, Alireza Foroumadi, Nader Sheibani and 1 more

Abstract read
In one paragraph

Article in International journal of biological macromolecules, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Azadeh Fallah-BagheriInstitute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Ali Akbar Saboury
Leila Ma'mani
Mohammad Taghizadeh
Reza Khodarahmi
Samira Ranjbar
Mousa Bohlooli
Abbas Shafiee
Alireza Foroumadi
Nader Sheibani
Ali Akbar Moosavi-Movahedi

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ROBERT W NICKELLS · 2005 to 2026
$12.6M
NEI NIH HHS P30 EY016665
6 · The paper itself

Abstract

Silica nanoparticle supported imidazolium ionic liquid [SNImIL] was synthesized and utilized as a biocompatible additive for studying the thermal reversibility of human carbonic anhydrase II (HCA II). For this purpose, we prepared additive by modification of nanoparticles through the grafting of ionic liquids on the surface of nanoparticles (SNImIL). The SNImIL were fully characterized by Fourier transform infrared spectroscopy, scanning electron microscopy and thermo gravimetric analysis. The characterization of HCA II was investigated by various techniques including UV-vis and ANS fluorescence spectrophotometry, differential scanning calorimetry, and docking study. SNImIL induced disaggregation, enhanced protein stability and increased thermal reversibility of HCA II by up to 42% at pH 7.75.

Indexed as

TemperatureCarbonic Anhydrase IIHumansImidazolesIonic LiquidsMolecular Docking SimulationNanoparticlesProtein MultimerizationProtein Structure, QuaternarySilicon DioxideCarbonic Anhydrase IIImidazolesIonic LiquidsSilicon Dioxide

Identifiers

PMID22829053
PMCPMC3677219

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.