Evidence map›Paper›PMID 22829016›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2012

Pre- and early in-hospital procedures in patients with acute coronary syndromes: first results of the "German chest pain unit registry".

Felix Post, Evangelos Giannitsis, Thomas Riemer, Lars S Maier, Claus Schmitt, Burghard Schumacher, Gerd Heusch, Harald Mudra, Thomas Voigtländer, Rainer Erbel and 6 more

Abstract read
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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Criteria of the German Society of Cardiology for the establishment of chest pain units: update 2014.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Guideline
  2. Trial
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Article
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  10. A patient with a rare cause of elevated troponin I.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Article
  11. [Chest pain units or chest pain algorithm?].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2014
    Review
  12. Uncommon cause of ST-segment elevation in V1-V3: incremental value of cardiac magnetic resonance imaging.Clinical research in cardiology : official journal of the German Cardiac Society · 2014
    Article
  13. Observational
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  19. Anti-glioma action of aloe emodin: the role of ERK inhibition.Cellular and molecular life sciences : CMLS · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 14 institutions in 1 country.

Felix Post2nd Department of Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.
Evangelos Giannitsis
Thomas Riemer
Lars S Maier
Claus Schmitt
Burghard Schumacher
Gerd Heusch
Harald Mudra
Thomas Voigtländer
Rainer Erbel
Harald Darius
Hugo Katus
Christian Hamm
Jochen Senges
Tommaso Gori
Thomas Münzel
Heidelberg University · DEUniversity Medical Center of the Johannes Gutenberg University Mainz · DECardiovascular Center Bethanien · DEDeutsches Herzzentrum München · DEEssen University Hospital · DEJohannes Gutenberg University Mainz · DEKerckhoff Klinik · DEMünchen Klinik Neuperlach · DEStädtisches Klinikum Karlsruhe · DEStiftung Institut für Herzinfarktforschung · DEUniversity Hospital Heidelberg · DEUniversity of Göttingen · DEVivantes Klinikum · DEWestpfalz Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn an attempt to improve the treatment of patients with acute coronary syndromes (ACS), a network of certified chest pain units (CPUs) has been recently established in Germany.

methodsData from patients admitted between December 2008 and September 2011 for ACS in 40 certified CPUs participating in the registry were prospectively collected.

resultsA total of 5,457 patients was admitted for ACS; 798 patients (14.6 %) were diagnosed with an ST-elevation myocardial infarction (STEMI), 2,244 (41.1 %) with a non-ST-elevation myocardial infarction (NSTEMI), and 2,415 (44.3 %) with unstable angina. The mean time to first medical contact was 2:08 h for STEMI patients. A pre-hospital ECG was available in 23.8 % of all ACS patients. Importantly, evidence of ST-segment elevation was present in 79.7 % of the STEMI patients already in this pre-hospital ECG. As many as 76.6 % of the patients, independently of their symptoms and final diagnosis, received an ECG within 10 min of reaching the CPU. 98.2 % of STEMI patients underwent invasive diagnostics, with an in-hospital delay as little as 31 (11-75) min.

conclusionThe establishment of a nation-wide network of certified CPUs optimizes the medical treatment of patients with ACS while providing an ideal infrastructure to evaluate and improve, both on a nation-wide and a single center scale, the adherence to guidelines. The median delay between symptom onset and first medical contact remains high. Although performed relatively rarely, a pre-hospital ECG facilitates earlier diagnosis of a STEMI in a large majority of patients. The introduction of CPUs minimizes in-hospital delays and exploits the benefit of invasive diagnostics and treatment.

Indexed as

Acute Coronary SyndromeAgedAngina, UnstableChest PainCoronary Care UnitsElectrocardiographyGermanyGuideline AdherenceHumansMaleMiddle AgedMyocardial InfarctionPractice Guidelines as TopicProspective StudiesQuality Assurance, Health CareRegistries

Identifiers

PMID22829016
OpenAlexW2171521008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.