Evidence map›Paper›PMID 22827946›Full record

ArticlePlant signaling & behavior2012

The function of calreticulin in plant immunity: new discoveries for an old protein.

Yongjian Qiu, Jing Xi, Liqun Du, B W Poovaiah

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 48 citations in OpenAlex.

  1. Long-Term Phytaspase Responses inInternational journal of molecular sciences · 2025
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  2. Proteome-Level Investigation ofInternational journal of molecular sciences · 2023
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  11. Transcriptome dynamics underlying elicitor-induced defense responses against Septoria leaf spot disease of tomato (Physiology and molecular biology of plants : an international journal of functional plant biology · 2021
    Article
  12. Article
  13. HaCRT1 ofFrontiers in plant science · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yongjian QiuDepartment of Horticulture, Washington State University, Pullman, Washington, USA.
Jing Xi
Liqun Du
B W Poovaiah
Washington State University · USHangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its initial discovery as a high affinity Ca ( 2+) -binding protein in the sarcoplasmic reticulum and endoplasmic reticulum (ER), calreticulin (CRT) has been documented to be a multifunctional protein in both animal and plant cells. This protein is well recognized as a Ca ( 2+) -binding molecular chaperone that facilitates the folding of newly synthesized glycoproteins and regulates the Ca ( 2+) homeostasis in the ER lumen. However, functional relevance associated with its localization in other cellular compartments has also been reported. Recent studies suggest that both isoforms of plant CRTs (AtCRT1/2 and AtCRT3) are involved in regulating plant defense against biotrophic pathogens. Here we discuss the cellular functions of CRT and its connection to the emerging functions of AtCRTs in plant immunity.

Indexed as

Plant ImmunityAmino Acid SequenceAnimalsArabidopsisArabidopsis ProteinsCalreticulinHumansMolecular Sequence DataMutationPhenotypePlants, Genetically ModifiedProtein TransportSubcellular FractionsArabidopsis ProteinsCalreticulin

Identifiers

PMID22827946
PMCPMC3474682
OpenAlexW2043493695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.