ArticleBMC microbiology2012
Indication for Co-evolution of Lactobacillus johnsonii with its hosts.
Article in BMC microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Probiotic Lactobacillus johnsonii RS-7 Alleviates Intestinal Inflammation Via the TLR4/MyD88/NF-κB Signaling Pathway.Probiotics and antimicrobial proteins · 2026Article
- Direct-fed Microbials (DFM) and Poultry Genomics: A Synergistic Approach to Sustainable Antibiotic Free Farming.Probiotics and antimicrobial proteins · 2026Review
- Strain-resolved biology ofFrontiers in veterinary science · 2026Review
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- Bacterial guilds, not genus-level taxa, mediate the protective effects of time-restricted feeding against high-fat diet-induced obesity in mice.ISME communications · 2025Article
- Unveiling the potential ofFrontiers in microbiology · 2025Review
- Genome sequence ofMicrobiology resource announcements · 2024Article
- Genomic analysis and functional properties ofFrontiers in microbiology · 2024Article
- Survey of antimicrobial and probiotic use practices in wildlife rehabilitation in the United States.PloS one · 2024Article
- The Effects ofMicroorganisms · 2023Review
- Milk oligosaccharide-mediated cross-feeding betweenBioscience of microbiota, food and health · 2021Article
- Article
- Non-ViableFoods (Basel, Switzerland) · 2020Article
- PCR-based screening, isolation, and partial characterization of motile lactobacilli from various animal feces.BMC microbiology · 2020Article
- Comparative Genomics Analysis ofGenes · 2020Article
- Comparative genomic analysis of Proteus spp. isolated from tree shrews indicated unexpectedly high genetic diversity.PloS one · 2020Article
- A novel probiotic, Lactobacillus johnsonii 456, resists acid and can persist in the human gut beyond the initial ingestion period.Gut microbes · 2019Article
- The evolution of ecological facilitation within mixed-species biofilms in the mouse gastrointestinal tract.The ISME journal · 2018Article
- The Genomic Basis of Lactobacilli as Health-Promoting Organisms.Microbiology spectrum · 2017Review
- Draft Genome Sequence of Lactobacillus johnsonii Strain 16, Isolated from Mice.Genome announcements · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe intestinal microbiota, composed of complex bacterial populations, is host-specific and affected by environmental factors as well as host genetics. One important bacterial group is the lactic acid bacteria (LAB), which include many health-promoting strains. Here, we studied the genetic variation within a potentially probiotic LAB species, Lactobacillus johnsonii, isolated from various hosts.
resultsA wide survey of 104 fecal samples was carried out for the isolation of L. johnsonii. As part of the isolation procedure, terminal restriction fragment length polymorphism (tRFLP) was performed to identify L. johnsonii within a selected narrow spectrum of fecal LAB. The tRFLP results showed host specificity of two bacterial species, the Enterococcus faecium species cluster and Lactobacillus intestinalis, to different host taxonomic groups while the appearance of L. johnsonii and E. faecalis was not correlated with any taxonomic group. The survey ultimately resulted in the isolation of L. johnsonii from few host species. The genetic variation among the 47 L. johnsonii strains isolated from the various hosts was analyzed based on variation at simple sequence repeats (SSR) loci and multi-locus sequence typing (MLST) of conserved hypothetical genes. The genetic relationships among the strains inferred by each of the methods were similar, revealing three different clusters of L. johnsonii strains, each cluster consisting of strains from a different host, i.e. chickens, humans or mice.
conclusionsOur typing results support phylogenetic separation of L. johnsonii strains isolated from different animal hosts, suggesting specificity of L. johnsonii strains to their hosts. Taken together with the tRFLP results, that indicated the association of specific LAB species with the host taxonomy, our study supports co-evolution of the host and its intestinal lactic acid bacteria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.