Evidence map›Paper›PMID 22827803›Full record

SynthesisBMC medical imaging2012

Is single reading with computer-aided detection (CAD) as good as double reading in mammography screening? A systematic review.

Edward Azavedo, Sophia Zackrisson, Ingegerd Mejàre, Marianne Heibert Arnlind

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC medical imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Neoadjuvant chemotherapy of breast cancer with pirarubicin versus epirubicin in combination with cyclophosphamide and docetaxel.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Trial
  2. Trial
  3. Article
  4. Article
  5. Framing the fallibility of Computer-Aided Detection aids cancer detection.Cognitive research: principles and implications · 2023
    Article
  6. Review
  7. The optimal use of computer aided detection to find low prevalence cancers.Cognitive research: principles and implications · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Digital Analysis in Breast Imaging.Breast care (Basel, Switzerland) · 2019
    Review
  16. Article
  17. Deep neural network improves fracture detection by clinicians.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edward AzavedoDepartment of Diagnostic Radiology, Karolinska Institutet, Stockholm, Sweden.
Sophia Zackrisson
Ingegerd Mejàre
Marianne Heibert Arnlind

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn accordance with European guidelines, mammography screening comprises independent readings by two breast radiologists (double reading). CAD (computer-aided detection) has been suggested to complement or replace one of the two readers (single reading + CAD).The aim of this systematic review is to address the following question: Is the reading of mammographic x-ray images by a single breast radiologist together with CAD at least as accurate as double reading?

methodsThe electronic literature search included the databases Pub Med, EMBASE and The Cochrane Library. Two independent reviewers assessed abstracts and full-text articles.

results1049 abstracts were identified, of which 996 were excluded with reference to inclusion and exclusion criteria; 53 full-text articles were assessed for eligibility. Finally, four articles were included in the qualitative analysis, and one in a GRADE synthesis.

conclusionsThe scientific evidence is insufficient to determine whether the accuracy of single reading + CAD is at least equivalent to that obtained in standard practice, i.e. double reading where two breast radiologists independently read the mammographic images.

Indexed as

Breast NeoplasmsFemaleHumansMammographyMass ScreeningObserver VariationPattern Recognition, AutomatedPrevalenceRadiographic Image Interpretation, Computer-AssistedReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID22827803
PMCPMC3464719

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.