Evidence map›Paper›PMID 22825825›Full record

ArticleJournal of medical virology2012

Dynamics of urinary polyomavirus shedding in healthy adult women.

Courtney L Kling, Alexandra T Wright, Sophie E Katz, Gloria B McClure, J Suzette Gardner, Jason T Williams, Natalie M Meinerz, Robert L Garcea, John A Vanchiere

Abstract read
In one paragraph

Article in Journal of medical virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. A multicenter prospective study to define the natural history of BK viral infections in kidney transplantation.Transplant infectious disease : an official journal of the Transplantation Society · 2024
    Observational
  7. Optimized amplification of BK polyomavirus in urine.Journal of virological methods · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Human polyomavirus KI, WU, BK, and JC in healthy volunteers.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  12. Fecal Polyomavirus Excretion in Infancy.Journal of the Pediatric Infectious Diseases Society · 2016
    Article
  13. The polyomavirus puzzle: is host immune response beneficial in controlling BK virus after adult hematopoietic cell transplantion?Transplant infectious disease : an official journal of the Transplantation Society · 2014
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Courtney L KlingSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Alexandra T Wright
Sophie E Katz
Gloria B McClure
J Suzette Gardner
Jason T Williams
Natalie M Meinerz
Robert L Garcea
John A Vanchiere
Louisiana State University Health Sciences Center Shreveport · USUniversity of Colorado Boulder · USLouisiana State University in Shreveport · US

Funding

RECRUITMENT YEAR FOR PI#5P20RR018724 · NCRR · LOUISIANA STATE UNIV HSC SHREVEPORT · PI KIM, SEONG K · 2003 to 2011
$16.1M
COBRE Center for Molecular and Tumor VirologyP20GM103433 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI O'CALLAGHAN, DENNIS JOHN · 2012 to 2012
$1.9M
NCRR NIH HHS 5P20RR018724-10NCRR NIH HHS P20 RR018724NIGMS NIH HHS 8P20GM103433-10NIGMS NIH HHS P20 GM103433
6 · The paper itself

Abstract

The hypothesis was examined that physiologic variation of estrogen concentrations during the menstrual cycle can provoke BK virus (BKV) excretion. BKV and JCV viral loads were determined in urine specimens obtained almost daily from 20 healthy, non-pregnant women over 2 months. Asymptomatic urinary shedding of BKV was observed in 123 (12.0%) of 1,021 specimens from 11 (55%) study subjects. Two subjects excreted JCV in their urine, with one subject excreting detectable JCV in all urine specimens. Analysis of 36 complete menstrual cycles revealed no difference in the prevalence of BKV excretion between pre-ovulatory and post-ovulatory phases of the menstrual cycle. The unexpected day-to-day variability in BKV excretion suggests that as yet unidentified factors may contribute to the periodic shedding of BKV by healthy women.

Indexed as

Virus SheddingAdultAntibodies, ViralAsymptomatic InfectionsBK VirusFemaleHumansJC VirusMenstrual CyclePolyomavirus InfectionsTumor Virus InfectionsViral LoadVirus ReplicationYoung AdultAntibodies, Viral

Identifiers

PMID22825825
PMCPMC4010311
OpenAlexW2071993570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.