SynthesisHernia : the journal of hernias and abdominal wall surgery2012
Systematic review and meta-analysis on heavy and lightweight polypropylene mesh in Lichtenstein inguinal hernioplasty.
Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Uniformity of Chronic Pain Assessment after Inguinal Hernia Repair: A Critical Review of the Literature.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2017Pooled it
- Update with level 1 studies of the European Hernia Society guidelines on the treatment of inguinal hernia in adult patients.Hernia : the journal of hernias and abdominal wall surgery · 2014Guideline
- Chronic pain after open inguinal hernia repair: expertise-based randomized clinical trial of heavyweight or lightweight mesh.The British journal of surgery · 2021Trial
- Factors predicting chronic pain after open inguinal hernia repair: a regression analysis of randomized trial comparing three different meshes with three fixation methods (FinnMesh Study).Hernia : the journal of hernias and abdominal wall surgery · 2018Trial
- Pain and quality of life after inguinal hernia surgery: a multicenter randomized controlled trial comparing lightweight vs heavyweight mesh (Supermesh Study).Updates in surgery · 2018Trial
- Three-month results of the effect of Ultrapro or Prolene mesh on post-operative pain and well-being following endoscopic totally extraperitoneal hernia repair (TULP trial).Surgical endoscopy · 2015Trial
- Lightweight versus heavyweight synthetic mesh for inguinal hernia repair.The Cochrane database of systematic reviews · 2025Article
- Article
- Mesh infection in cases of polypropylene mesh hernioplasty.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- Causes of recurrences after open inguinal herniorrhaphy.Hernia : the journal of hernias and abdominal wall surgery · 2019Review
- Chronic pain, discomfort, quality of life and impact on sex life after open inguinal hernia mesh repair: an expertise-based randomized clinical trial comparing lightweight and heavyweight mesh.Hernia : the journal of hernias and abdominal wall surgery · 2018Article
- Surgical risk factors for recurrence in inguinal hernia repair - a review of the literature.Innovative surgical sciences · 2017Review
- Laparoscopic transabdominal inguinal hernia repair in community hospital settings: a general surgeon's last 10 years experience.Hernia : the journal of hernias and abdominal wall surgery · 2014Article
- Early and late postoperative inflammatory and collagen deposition responses in three different meshes: an experimental study in rats.Hernia : the journal of hernias and abdominal wall surgery · 2014Article
- Invited commentary: Persistent pain after inguinal hernia repair: what do we know and what do we need to know?Hernia : the journal of hernias and abdominal wall surgery · 2013Article
- Meta-analyses of lightweight versus conventional (heavy weight) mesh in inguinal hernia surgery.Hernia : the journal of hernias and abdominal wall surgery · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecurrence and pain are the two most important outcomes after inguinal hernia surgery. The concept of lightweight or partially absorbable macroporous meshes was developed under the assumption that the observed pain rate could be decreased without increasing the number of recurrences. Few randomized trials were published to analyze their clinical value, and some concern was raised because of an increased risk of recurrence. A systematic review and a meta-analysis of RCTs were carried out to determine whether the use of lightweight meshes influenced the pain and recurrence rate after Lichtenstein hernioplasty.
methodsTo assess the value of the lightweight mesh, an extensive literature search was performed. The random-effect meta-analysis model was used to correct for clinical diversity and methodological variations between studies. Recurrence rate, aspects of chronic pain and foreign body feeling at 6-60 months postoperatively were assessed.
resultsEight prospective RCTs of good quality were identified. Analysis demonstrated no significant difference regarding recurrence (OR, 1.11; 95 % CI, 0.57-2.14; p = 0.77). No significant difference was observed concerning severe pain (OR, 0.99; 95 % CI, 0.48-2.02; p = 0.97). Description of any pain resulted in a significant improvement in the lightweight group (OR, 0.65; 95 % CI, 0.50-0.84; p = 0.001). The presence of foreign body feeling was favoring the lightweight group (OR, 0.62; 95 % CI, 0.41-0.94; p = 0.02).
conclusionsThe use of lightweight mesh did not neither increase the recurrence rate nor reduce the incidence of severe pain. A significant reduction in foreign body feeling and overall pain rate in the postoperative period was recorded. Lightweight meshes could be considered as a material of choice in primary inguinal hernioplasty.
Indexed as
Identifiers
22824988What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.