ReviewHuman reproduction (Oxford, England)2012
Relevance of vitamin D in reproduction.
Review in Human reproduction (Oxford, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 176 citations in OpenAlex.
- Air pollutants and ovarian reserve: a systematic review of the evidence.Frontiers in public health · 2024Pooled it
- A systematic review and meta-analysis of the association between vitamin D and ovarian reserve.Scientific reports · 2021Pooled it
- Vitamin D metabolites across the menstrual cycle: a systematic review.BMC women's health · 2019Pooled it
- Trial
- Acute Supplementation with High Dose Vitamin D3 Increases Serum Anti-Müllerian Hormone in Young Women.Nutrients · 2017Trial
- Trial
- Unveiling the Role of Vitamin D/VDR in Promoting Endometrial Decidualization.International journal of endocrinology · 2026Article
- Association of Deficiency in Vitamin D, Vitamin E, and Selenium Levels With Premature Ovarian Insufficiency: A Systematic Review.Health science reports · 2025Review
- A disturbed communication between hypothalamic-pituitary-ovary axis and gut microbiota in female infertility: is diet to blame?Journal of translational medicine · 2025Review
- Article
- Association between serum 25-hydroxyvitamin D and antimüllerian hormone levels in a cohort of African-American women.Fertility and sterility · 2024Article
- Observational
- Serum vitamin D in sanctuary chimpanzees (Pan troglodytes) in range countries: A pilot study.Veterinary medicine and science · 2023Article
- Vitamin D status during pregnancy: a role in intergenerational reproductive health?European journal of epidemiology · 2023Article
- Severity of Menstrual Pain Is Associated with Nutritional Intake and Lifestyle Habits.Healthcare (Basel, Switzerland) · 2023Article
- Vitamin D receptor expression in sperm of males with unexplained infertility.Caspian journal of internal medicine · 2023Article
- An Overview of the Current Known and Unknown Roles of Vitamin DInternational journal of molecular sciences · 2022Review
- Using follicular fluid metabolomics to investigate the association between air pollution and oocyte quality.Environment international · 2022Article
- Preconception vitamin D and miscarriage in a prospective cohort study.Human reproduction (Oxford, England) · 2022Article
- Vitamin D status is heritable and under environment-dependent selection in the wild.Molecular ecology · 2022Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The steroid hormone vitamin D is historically recognized for its relevance to bone health and calcium homeostasis. Recent years have witnessed a shift in focus to non-skeletal benefits of vitamin D; in this latter context, an accruing body of literature attests to a relevance of vitamin D to reproductive physiology. This article reviews the existing data about the diverse and previously underappreciated roles for vitamin D in reproductive health. A large body of available literature suggests that vitamin D deficiency may be detrimental to reproductive biology. However, given that our appreciation of vitamin D's role in reproductive physiology is almost entirely shaped by 'associative' studies and that data based on prospective interventional trials are limited, these concepts remain predominantly conjectural. Exact mechanisms whereby vitamin D may participate in the regulation of reproductive physiology remain far from clear. This review underscores a need for appropriately designed intervention trials to address the existing knowledge gaps and to delineate the specific roles of vitamin D signaling in reproductive biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.