Evidence map›Paper›PMID 22823178›Full record

SynthesisAddiction (Abingdon, England)2012

Racial/ethnic disparities in HIV infection among people who inject drugs: an international systematic review and meta-analysis.

Don C Des Jarlais, Heidi A Bramson, Cherise Wong, Karla Gostnell, Javier Cepeda, Kamyar Arasteh, Holly Hagan

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Addiction (Abingdon, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic review: methodological flaws in racial/ethnic reporting for gastroesophageal reflux disease.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2018
    Pooled it
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  6. HIV's Trajectory: Biomedical Triumph, Structural Failure.American journal of public health · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Don C Des JarlaisThe Baron Edmond de Rothschild Chemical Dependency Institute, Beth Israel Medical Center, New York, NY 10038, USA. ddesjarlais@chpnet.org
Heidi A Bramson
Cherise Wong
Karla Gostnell
Javier Cepeda
Kamyar Arasteh
Holly Hagan

Funding

HIV Infection in Ethnic Minority IDUs: An International Systematic ReviewR01DA024612 · NIDA · BETH ISRAEL MEDICAL CTR (NEW YORK) · PI DES JARLAIS, DON C · 2008 to 2011
$2.0M
NIDA NIH HHS 5R01DA024612NIDA NIH HHS R01 DA024612
6 · The paper itself

Abstract

aimsThe Ethnic Minority Meta-Analysis (EMMA) aims to assess racial/ethnic disparities in HIV infection among people who inject drugs (PWID) across various countries. This is the first report of the data.

methodsStandard systematic review/meta-analysis methods were utilized, including searching for, screening and coding published and unpublished reports and meta-analytical statistics. We followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement and Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines for reporting methods. Disparities were measured with the odds ratio (OR) for HIV prevalence among ethnic minority PWID compared to ethnic majority PWID; an OR >1.0 indicated higher prevalence among ethnic minorities.

resultsRacial/ethnic disparities in HIV prevalence among PWID were examined in 131 prevalence reports, with 214 racial/ethnic minority to majority comparisons, comprising 106 715 PWID. Overall, the pooled OR indicates an increased likelihood of higher HIV prevalence among racial/ethnic minority compared to racial/ethnic majority PWID [OR = 2.09, 95% confidence interval (CI): 1.92-2.28]. Among 214 comparisons, 106 produced a statistically significant higher OR for minorities; in 102 comparisons the OR was not significantly different from 1.0; six comparisons produced a statistically significant higher OR for majority group members. Disparities were particularly large in the United States, pooled OR = 2.22 (95% CI: 2.03-2.44). There was substantial variation in ORs-I(2)  = 75.3%: interquartile range = 1.38-3.56-and an approximate Gaussian distribution of the log ORs.

conclusionsAmong people who inject drugs, ethnic minorities are approximately twice as likely to be HIV seropositive than ethnic majorities. The great heterogeneity and Gaussian distribution suggest multiple causal factors and a need to tailor interventions to local conditions.

Indexed as

EthnicityGlobal HealthHIV InfectionsHumansMinority GroupsPrevalenceRacial GroupsSubstance Abuse, Intravenous

Identifiers

PMID22823178
PMCPMC3504180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.