Evidence map›Paper›PMID 22822483›Full record

ArticleChemical communications (Cambridge, England)2012

Time-gated luminescence microscopy with responsive nonmetal probes for mapping activity of protein kinases in living cells.

Angela Vaasa, Kadri Ligi, Shabnam Mohandessi, Erki Enkvist, Asko Uri, Lawrence W Miller

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Development of Time-Resolved Luminescence Measurement Instruments for Biosensing and Bioimaging - An Overview.Measurement : journal of the International Measurement Confederation · 2025
    Article
  2. Article
  3. Review
  4. How to build a time-gated luminescence microscope.Current protocols in cytometry · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Angela VaasaInstitute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
Kadri Ligi
Shabnam Mohandessi
Erki Enkvist
Asko Uri
Lawrence W Miller
University of Tartu · EEUniversity of Illinois Chicago · US

Funding

Targeted lanthanide contrast agents for in cellulo single molecule imagingR01GM081030 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MILLER, LAWRENCE · 2008 to 2018
$2.5M
NIGMS NIH HHS R01 GM081030NIGMS NIH HHS R01GM081030
6 · The paper itself

Abstract

A photoluminescence probe ARC-1185, possessing both high affinity towards basophilic protein kinases (PKs) and microsecond-scale luminescence lifetime when associated with a kinase, was used for the mapping of ARC-1185-PK complexes in living cells with time-gated luminescence microscopy.

Indexed as

Microscopy, FluorescenceAnimalsBasophilsDogsFluorescent DyesMadin Darby Canine Kidney CellsOligopeptidesProtein KinasesTime FactorsUltraviolet RaysARC-1185Fluorescent DyesOligopeptidesProtein Kinases

Identifiers

PMID22822483
PMCPMC3415249
OpenAlexW1976927357

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.