ArticleTranslational biomedicine2012
In vitro antiviral activity of honey against varicella zoster virus (VZV): A translational medicine study for potential remedy for shingles.
Article in Translational biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Honey for acute cough in children.The Cochrane database of systematic reviews · 2018Pooled it
- Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial.BMJ open · 2019Trial
- Clinical and Postoperative Applications of Manuka Honey in Wound Healing: An Evidence-Based Review.International wound journal · 2026Review
- Bee products as alternatives in the treatment of viral infections.Journal of the science of food and agriculture · 2026Review
- Exploring the potential of hydro alcoholic crude extract of beeswax as antibacterial antifungal antiviral antiinflammatory and antioxidant agent.Scientific reports · 2025Article
- Review on role of honey in disease prevention and treatment through modulation of biological activities.Open life sciences · 2025Review
- Hive Products: Composition, Pharmacological Properties, and Therapeutic Applications.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Natural products as a source of Coronavirus entry inhibitors.Frontiers in cellular and infection microbiology · 2024Review
- Quality of Commercially Available Manuka Honey Expressed by Pollen Composition, Diastase Activity, and Hydroxymethylfurfural Content.Foods (Basel, Switzerland) · 2023Article
- Physicochemical Characteristics and Bioactive Compounds of Different Types of Honey and Their Biological and Therapeutic Properties: A Comprehensive Review.Antibiotics (Basel, Switzerland) · 2023Review
- Evaluating leishmanicidal effects of Lucilia sericata products in combination with Apis mellifera honey using an in vitro model.PloS one · 2023Article
- Review
- Determination of Chestnut Honey Consumption Characteristics as a Traditional Treatment Method and Its Effect on Protection from COVID-19.Complementary medicine research · 2022Article
- Article
- Medical-Grade Honey Outperforms Conventional Treatments for Healing Cold Sores-A Clinical Study.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Pharmaceutical Prospects of Bee Products: Special Focus on Anticancer, Antibacterial, Antiviral, and Antiparasitic Properties.Antibiotics (Basel, Switzerland) · 2021Review
- Conventional and Organic Honeys as a Source of Water- and Ethanol-Soluble Molecules with Nutritional and Antioxidant Characteristics.Molecules (Basel, Switzerland) · 2021Article
- Biological Properties of Bee Bread Collected from Apiaries Located across Greece.Antibiotics (Basel, Switzerland) · 2021Article
- Fighting against the second wave of COVID-19: Can honeybee products help protect against the pandemic?Saudi journal of biological sciences · 2021Review
- Traditional foods with their constituent's antiviral and immune system modulating properties.Heliyon · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
objectivesThe aim of this study was to determine the in vitro anti-viral effect of honey on varicella zoster virus.
methodsManuka and clover honeys were used at concentrations ranging from 0-6% wt/vol. A clinical VZV isolate was obtained from a zoster vesicle and used at low passage. Various concentrations of manuka and clover honey were added to the tissue culture medium of VZV-infected human malignant melanoma (MeWo) cells.
resultsBoth types of honey showed antiviral activity against varicella zoster virus with an approximate EC50 = 4.5 % (wt/vol).
conclusionsOur results showed that honey has significant in vitro anti-VZV activity. As, honey is convenient for skin application, is readily available and inexpensive, honey may be an excellent remedy to treat zoster rash in developing countries where antiviral drugs are expensive or not easily available.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.