ArticleAnatomy & cell biology2012
Arginine vasopressin (AVP) expressional changes in the hypothalamic paraventricular and supraoptic nuclei of stroke-prone spontaneously hypertensive rats.
Article in Anatomy & cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- Vasopressin and cardiovascular autonomic adjustment in chronic hypertensive pregnancy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Effects of Saffron Extract (AffronNutrients · 2023Article
- Electroacupuncture and manual acupuncture at LR3 and ST36 have attenuating effects on hypertension and subsequent cognitive dysfunction in spontaneously hypertensive rats: A preliminary resting-state functional magnetic resonance imaging study.Frontiers in neuroscience · 2023Article
- An Overview of Similarities and Differences in Metabolic Actions and Effects of Central Nervous System Between Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) and Sodium Glucose Co-Transporter-2 Inhibitors (SGLT-2is).Diabetes, metabolic syndrome and obesity : targets and therapy · 2021 · on this mapReview
- Vasopressin and v1br gene expression is increased in the hypothalamic pvn of borderline hypertensive rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Review
- Vasopressin & Oxytocin in Control of the Cardiovascular System: An Updated Review.Current neuropharmacology · 2020Review
- Angiotensin ATAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2018Article
- A reduction in SK channels contributes to increased activity of hypothalamic magnocellular neurons during heart failure.The Journal of physiology · 2017Article
- Hypothalamic and inflammatory basis of hypertension.Clinical science (London, England : 1979) · 2017Review
- Hypothalamic signaling mechanisms in hypertension.Current hypertension reports · 2015Review
- Sex-dependent pathophysiology as predictors of comorbidity of major depressive disorder and cardiovascular disease.Pflugers Archiv : European journal of physiology · 2013Review
- Vasopressin and oxytocin in control of the cardiovascular system.Current neuropharmacology · 2013Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arginine vasopressin (AVP) is a neuropeptide with vasoconstrictive, antidiuretic, cardiovascular regulative and hepatic glycogenolysis effects, that also affects other behaviors including modulating learning. A number of studies on AVP regulation have been conducted in various metabolic diseases (disorders). In this study, the immunoreactivities of AVP in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) and mRNA expressions in the hypothalamus were investigated by immunohistochemistry and quantitative real-time PCR (RT-qPCR) in stroke-prone spontaneously hypertensive rats at different ages (i.e., at postnatal months [PM] 1, 8, and 12). Blood glucose levels in the PM 8 group were higher than in the other groups. However, cresyl violet positive neurons were detected in the PVN and SON of all animals, and numbers of cresyl violet positive neurons were similar in all aged groups. In addition, AVP immunoreactivity was detected in the PVN and SON of all age groups, and AVP immunoreactivity and mRNA expression levels were found to be increased in proportion to age by immunohistochemistry and RT-qPCR. These results suggest that the diabetic condition is temporally generated after hypertension has developed. Furthermore, our findings suggest that increased AVP expressions in the hypothalamic PVN and SON are associated with hypertension by age.
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