ArticleSoft matter2012
Ion Electrodiffusion Governs Silk Electrogelation.
Article in Soft matter, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
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Who cites it
21 citing papers in PubMed.
- Preparation, Structure and Rheological Properties of Konjac Glucomannan-CaClGels (Basel, Switzerland) · 2026Article
- Degumming Time Governs Self-Assembled Silk Fibroin Hydrogel Properties through Molecular Weight and Amino Acid Composition.Biomacromolecules · 2025Article
- Development of Scalable Elastic Gelatin Hydrogel Films Crosslinked with Waterborne Polyurethane for Enhanced Mechanical Properties and Strain Recovery.Gels (Basel, Switzerland) · 2025Article
- Review of Spider Silk Applications in Biomedical and Tissue Engineering.Biomimetics (Basel, Switzerland) · 2024Review
- Silk-protein-based gradient hydrogels with multimode reprogrammable shape changes for biointegrated devices.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- An Overview of Recent Progress in Engineering Three-Dimensional Scaffolds for Cultured Meat Production.Foods (Basel, Switzerland) · 2023Review
- Silk fibroin hydrogels for biomedical applications.Smart medicine · 2022Review
- Impact of silk hydrogel secondary structure on hydrogel formation, silk leaching and in vitro response.Scientific reports · 2022Article
- Tannic acid: a crosslinker leading to versatile functional polymeric networks: a review.RSC advances · 2022Review
- Electrophoretic deposition of silk fibroin coatings with pre-defined architecture to facilitate precise control over drug delivery.Bioactive materials · 2021Article
- Electrodeposited Assembly of Additive-Free Silk Fibroin Coating from Pre-Assembled Nanospheres for Drug Delivery.ACS applied materials & interfaces · 2020Article
- Redox Is a Global Biodevice Information Processing Modality.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2019Article
- Electrobiofabrication: electrically based fabrication with biologically derived materials.Biofabrication · 2019Review
- Fusing Sensor Paradigms to Acquire Chemical Information: An Integrative Role for Smart Biopolymeric Hydrogels.Advanced healthcare materials · 2016Article
- Electrodeposited silk coatings for bone implants.Journal of biomedical materials research. Part B, Applied biomaterials · 2015Article
- A computational study of circulating large tumor cells traversing microvessels.Computers in biology and medicine · 2015Article
- Electrodeposited gels prepared from protein alloys.Nanomedicine (London, England) · 2015Article
- Processing and characterisation of a novel electropolymerized silk fibroin hydrogel membrane.Scientific reports · 2014Article
- High Throughput Screening of Dynamic Silk-Elastin-Like Protein Biomaterials.Advanced functional materials · 2014Article
- Transdermal delivery devices: fabrication, mechanics and drug release from silk.Small (Weinheim an der Bergstrasse, Germany) · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Silk electrogelation involves the transition of an aqueous silk fibroin solution to a gel state (E-gel) in the presence of an electric current. The process is based on local pH changes as a result of water electrolysis - generating H(+) and OH(-) ions at the (+) and (-) electrodes, respectively. Silk fibroin has a pI=4.2 and when local pH<pI, E-gel forms. An experimental system was constructed that allowed the measurement of E-gel growth and pH distribution for an applied current. To explain the observed rectangular pH profile of pH(gel)~4 surrounded by pH(silk-solution)~10, a finite-element ion electrodiffusion model was developed. The model relies on electrodiffusion of the generated H(+) and OH(-) ions. Initially, inputs into the model were the measured E-gel and voltage curves. The governing ion electrodiffusion equations were solved and the calculated pH matched the experimental pH profile, indicating that ion electrodiffusion dictates local pH changes and E-gel growth. Furthermore, the model predicted the constant currents (2mA and 3mA) necessary for two hypothetical E-gel growth curves and these results were then validated experimentally. The model thus shows how ion electrodiffusion governs the electrogelation process and also provides predictable outcomes for fundamental and practical E-gel applications.
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Registered trials
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