Alzheimer's disease, neuroprotection, and CNS immunosenescence.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed, 43 citations in OpenAlex.

1. Expression of GPR34 in microglia remains stable in human Alzheimer's disease.Acta neuropathologica · 2026
   Article
2. Entwined processes in Alzheimer's disease: Brain cellular senescence and Alzheimer's disease pathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
   Review
3. Emerging Microglial Therapies and Targets in Clinical Trial.Advances in neurobiology · 2024
   Review
4. Profiling Microglia in a Mouse Model of Machado-Joseph Disease.Biomedicines · 2022
   Article
5. Reduced Amygdala Microglial Expression of Brain-Derived Neurotrophic Factor and Tyrosine Kinase Receptor B (TrkB) in a Rat Model of Poststroke Depression.Medical science monitor : international medical journal of experimental and clinical research · 2020
   Article
6. The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut Feeling.Frontiers in aging neuroscience · 2019
   Review
7. Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans.Scientific reports · 2018
   Article
8. HIV-1-Associated Neurocognitive Disorders: Is HLA-C Binding Stability to βFrontiers in neurology · 2018
   Article
9. Mechanisms and regulation of neurotrophin synthesis and secretion.Neurosciences (Riyadh, Saudi Arabia) · 2016
   Review
10. Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation.Journal of neuroinflammation · 2015
    Article
11. Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity.Neuropharmacology · 2015
    Review
12. Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice.Oncotarget · 2015
    Article
13. Senescence-accelerated OXYS rats: a model of age-related cognitive decline with relevance to abnormalities in Alzheimer disease.Cell cycle (Georgetown, Tex.) · 2014
    Review
14. Neurodegenerative disorders: the Glia way forward.Frontiers in pharmacology · 2014
    Article
15. Microglia change from a reactive to an age-like phenotype with the time in culture.Frontiers in cellular neuroscience · 2014
    Article
16. Cardiorenal metabolic syndrome and diabetic cognopathy.Cardiorenal medicine · 2013
    Article
17. Carbonyl stress in aging process: role of vitamins and phytochemicals as redox regulators.Aging and disease · 2013
    Review
18. Microglia during development and aging.Pharmacology & therapeutics · 2013
    Review
19. T Cell Recruitment in the Brain during Normal Aging.Frontiers in cellular neuroscience · 2012
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors at 2 institutions in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

Indexed as