ArticleThe Plant cell2012
Interspecific RNA interference of SHOOT MERISTEMLESS-like disrupts Cuscuta pentagona plant parasitism.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed.
- Large-scale exchange of RNA between parasitic plant Orobanche cumana and its host Helianthus annuus.Pest management science · 2026Article
- Parasitic Plant-Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Gatekeepers and Gatecrashers of the Symplasm: Cross-Kingdom Effector Manipulation of Plasmodesmata in Plants.Plants (Basel, Switzerland) · 2025Review
- RNAi technology development for weed control: all smoke and no fire?Pest management science · 2025Review
- One organ to infect them all: the Cuscuta haustorium.Annals of botany · 2025Review
- Involvement of MID1-COMPLEMENTING ACTIVITY 1 encoding a mechanosensitive ion channel in prehaustorium development of the stem parasitic plant Cuscuta campestris.Plant & cell physiology · 2025Article
- Mobile RNAs as systemic signaling beyond boundaries for plant stress resistance.Frontiers in plant science · 2025Review
- Article
- The mRNA mobileome: challenges and opportunities for deciphering signals from the noise.The Plant cell · 2023Review
- The plant vampire diaries: a historic perspective on Cuscuta research.Journal of experimental botany · 2023Review
- Genomic and Epigenomic Mechanisms of the Interaction between Parasitic and Host Plants.International journal of molecular sciences · 2023Review
- Large-scale mRNA transfer betweeniScience · 2023Article
- CRISPR gene editing to improve crop resistance to parasitic plants.Frontiers in genome editing · 2023Review
- Comparative analysis ofFrontiers in plant science · 2023Article
- Insights into Mobile Small-RNAs Mediated Signaling in Plants.Plants (Basel, Switzerland) · 2022Review
- Review
- The master role of siRNAs in plant immunity.Molecular plant pathology · 2022Review
- Co-option of the SHOOT MERISTEMLESS network regulates protocorm-like body development in Phalaenopsis aphrodite.Plant physiology · 2022Article
- Molecular mechanisms underlying host-induced gene silencing.The Plant cell · 2022Review
- Bidirectional lncRNA Transfer betweenInternational journal of molecular sciences · 2022Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infection of crop species by parasitic plants is a major agricultural hindrance resulting in substantial crop losses worldwide. Parasitic plants establish vascular connections with the host plant via structures termed haustoria, which allow acquisition of water and nutrients, often to the detriment of the infected host. Despite the agricultural impact of parasitic plants, the molecular and developmental processes by which host/parasitic interactions are established are not well understood. Here, we examine the development and subsequent establishment of haustorial connections by the parasite dodder (Cuscuta pentagona) on tobacco (Nicotiana tabacum) plants. Formation of haustoria in dodder is accompanied by upregulation of dodder KNOTTED-like homeobox transcription factors, including SHOOT MERISTEMLESS-like (STM). We demonstrate interspecific silencing of a STM gene in dodder driven by a vascular-specific promoter in transgenic host plants and find that this silencing disrupts dodder growth. The reduced efficacy of dodder infection on STM RNA interference transgenics results from defects in haustorial connection, development, and establishment. Identification of transgene-specific small RNAs in the parasite, coupled with reduced parasite fecundity and increased growth of the infected host, demonstrates the efficacy of interspecific small RNA-mediated silencing of parasite genes. This technology has the potential to be an effective method of biological control of plant parasite infection.
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