ReviewAmerican journal of physiology. Heart and circulatory physiology2012
Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes.
Review in American journal of physiology. Heart and circulatory physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.
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Who cites it
133 citing papers in PubMed.
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- Optical mapping: pioneering the frontier of preclinical antiarrhythmic drug evaluation.iScience · 2026Review
- Versatile hiPSC Models and Bioengineering Platforms for Investigation of Atrial Fibrosis and Fibrillation.Cells · 2026Review
- A novel methodology to characterize beat-to-beat alternations in whole-cell calcium currents.PloS one · 2026Article
- Refining fibroblast-to-cardiomyocyte transdifferentiation protocols to explore emergent self-organization in cardiac cultures.PloS one · 2026Article
- Scalable differentiation of human cardiac organoids from iPSCs generates cardiac tissues for cardiac cell therapy.Theranostics · 2026Article
- Engineered heart tissues formed with cardiac progenitors and differentiated cardiomyocytes exhibit similar physiologic properties at differentiation-matched timepoints.Biofabrication · 2025Article
- Non-Invasive Mapping of Ventricular Action Potential Reconstructed from Contactless Magnetocardiographic Recordings in Intact and Conscious Guinea Pigs.Journal of cardiovascular development and disease · 2025Article
- CoordinatedeLife · 2025Article
- Interaction of cardiomyocytes from CCND2-overexpressing human induced pluripotent stem cells with electrically conductive hydrogels.RSC advances · 2025Article
- Atrial electrical alterations with intact cardiac structure and contractile function in a mouse model of an HCM-linkedJournal of molecular and cellular cardiology plus · 2025Article
- Label-free optical mapping for large-area biomechanical dynamics of multicellular systems.Biosensors & bioelectronics · 2025Article
- Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction.Nature communications · 2025Article
- Quantifying APD-ARI Differences Across Endo-Epicardial Surfaces in Human and Porcine Hearts.Computing in cardiology · 2025Article
- Acute ischaemia and gap junction modulation modify propagation patterns across Purkinje-myocardial junctions.Frontiers in physiology · 2025Article
- Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes.Nature communications · 2024Article
- Empagliflozin rescues pro-arrhythmic and CaScientific reports · 2024Article
- Evaluation of novel open-source software for cardiac optical mapping.Journal of molecular and cellular cardiology plus · 2024Article
- Inhibition of IL-1 Ameliorates Cardiac Dysfunction and Arrhythmias in a Murine Model of Kawasaki Disease.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
73 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
Optical mapping has become an increasingly important tool to study cardiac electrophysiology in the past 20 years. Multiple methods are used to process and analyze cardiac optical mapping data, and no consensus currently exists regarding the optimum methods. The specific methods chosen to process optical mapping data are important because inappropriate data processing can affect the content of the data and thus alter the conclusions of the studies. Details of the different steps in processing optical imaging data, including image segmentation, spatial filtering, temporal filtering, and baseline drift removal, are provided in this review. We also provide descriptions of the common analyses performed on data obtained from cardiac optical imaging, including activation mapping, action potential duration mapping, repolarization mapping, conduction velocity measurements, and optical action potential upstroke analysis. Optical mapping is often used to study complex arrhythmias, and we also discuss dominant frequency analysis and phase mapping techniques used for the analysis of cardiac fibrillation.
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