ArticleAJNR. American journal of neuroradiology2013
Microcatheter to recanalization (procedure time) predicts outcomes in endovascular treatment in patients with acute ischemic stroke: when do we stop?
Article in AJNR. American journal of neuroradiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Procedure time and clinical outcomes after thrombectomy: a pooled cohort analysis of three randomised trials.European stroke journal · 2026Trial
- Procedure time and outcomes in acute ischemic stroke with anterior circulation large vessel occlusion in the early and late time windows: A stratified analysis by onset-to-puncture time.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Association of Procedure Time With Clinical and Procedural Outcome in Patients With Basilar Occlusion Undergoing Embolectomy.Neurology · 2023Article
- Availability of tracheal shift in the chest X-ray image as pre-treatment evaluation of mechanical thrombectomy.The neuroradiology journal · 2022Article
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- Impact of Aortic Arch Anatomy on Technical Performance and Clinical Outcomes in Patients with Acute Ischemic Stroke.AJNR. American journal of neuroradiology · 2020Article
- Influence of procedure time on outcome and hemorrhagic transformation in stroke patients undergoing thrombectomy.Journal of neurology · 2019Article
- There Is No Association Between the Number of Stent Retriever Passes and the Incidence of Hemorrhagic Transformation for Patients Undergoing Mechanical Thrombectomy.Frontiers in neurology · 2019Article
- Intermediate Catheters Reduce the Length of Mechanical Thrombectomy Procedures in Acute Basilar Artery Occlusions.Clinical neuroradiology · 2016Article
- Carotid Elongation Does Not Affect Angiographic Results of Mechanical Thrombectomy in Acute Stroke.Clinical neuroradiology · 2016Article
- Histopathological Characteristics of IV Recombinant Tissue Plasminogen -Resistant Thrombi in Patients with Acute Ischemic Stroke.Journal of vascular and interventional neurology · 2016Article
- Impact of time-to-reperfusion on outcome in patients with poor collaterals.AJNR. American journal of neuroradiology · 2015Article
- Differentiating intraparenchymal hemorrhage from contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients undergoing endovascular treatment.Neuroradiology · 2014Article
- Aortic arch calcification, procedural times, and outcomes of endovascular treatment in patients with acute ischemic stroke.Journal of vascular and interventional neurology · 2014Article
- Complications of mechanical thrombectomy for acute ischemic stroke-a retrospective single-center study of 176 consecutive cases.Neuroradiology · 2014Article
- Pattern of informed consent acquisition in patients undergoing emergent endovascular treatment for acute ischemic stroke.Journal of vascular and interventional neurology · 2014Article
- Endovascular treatment for acute ischemic stroke patients: implications and interpretation of IMS III, MR RESCUE, and SYNTHESIS EXPANSION trials: A report from the Working Group of International Congress of Interventional Neurology.Journal of vascular and interventional neurology · 2014Article
- Fate of the penumbra after mechanical thrombectomy.AJNR. American journal of neuroradiology · 2014Article
- Direct carotid puncture in acute ischaemic stroke intervention.Stroke and vascular neurologyReview
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Authors and funding
7 authors.
Funding
Abstract
background and purposeEndovascular treatment for acute ischemic stroke consists of various mechanical and pharmacologic modalities used for recanalization of arterial occlusions. We performed this study to determine the relationship among procedure time, recanalization, and clinical outcomes in patients with acute ischemic stroke undergoing endovascular treatment. MATERIALS AND
methodsWe analyzed data from consecutive patients with acute ischemic stroke who underwent endovascular treatment during a 6-year period. Demographic characteristics, NIHSS score before and 24 hours after the procedure, and discharge mRS score were ascertained. Procedure time was defined by the time interval between microcatheter placement and recanalization or completion of the procedure. We estimated the procedure time after which favorable clinical outcome was unlikely, even after adjustment for age, time from symptom onset, and admission NIHSS scores.
resultsWe analyzed 209 patients undergoing endovascular treatment (mean age, 65 ± 16 years; 109 [52%] men; mean admission/preprocedural NIHSS score, 15.3 ± 6.8). Complete or partial recanalization was observed in 176 (84.2%) patients, while unfavorable outcome (mRS 3-6) was observed in 138 (66%) patients at discharge. In univariate analysis, patients with procedure time ≤30 minutes had lower rates of unfavorable outcome at discharge compared with patients with procedure time ≥30 minutes (52.3% versus 72.2%, P = .0049). In our analysis, the rates of favorable outcomes in endovascularly treated patients after 60 minutes were lower than rates observed with placebo treatment in the Prourokinase for Acute Ischemic Stroke Trial. In logistic regression analysis, unfavorable outcome was positively associated with age (P = .0012), admission NIHSS strata (P = .0017), and longer procedure times (P = .0379).
conclusionsProcedure time in patients with acute ischemic stroke appears to be a critical determinant of outcomes following endovascular treatment. This highlights the need for procedure time guidelines for patients being considered for endovascular treatment in acute ischemic stroke.
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