ArticleEnvironmental science and pollution research international2013
Screening of endocrine-disrupting phenols, herbicides, steroid estrogens, and estrogenicity in drinking water from the waterworks of 35 Italian cities and from PET-bottled mineral water.
Article in Environmental science and pollution research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- Bisphenol A exposure and associations with obesity among adults: a critical review.Public health nutrition · 2015Pooled it
- Effect-Based Assessment of the Quality and Potential Presence of Hazardous Chemical Pollutants in Drinking and Potable Water in Mexico City.ACS ES&T water · 2026Article
- Bisphenol A migration and associated health risk in polyethylene terephthalate-bottled yogurt drinks (Doogh) under different storage scenarios.Scientific reports · 2025Article
- Bisphenol A (BPA) toxicity assessment and insights into current remediation strategies.RSC advances · 2024Review
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- Bottled water contaminant exposures and potential human effects.Environment international · 2023Article
- Monitoring of Pollutants Content in Bottled and Tap Drinking Water in Italy.Molecules (Basel, Switzerland) · 2022Article
- Influence of Temperature on the Quantity of Bisphenol A in Bottled Drinking Water.International journal of environmental research and public health · 2022Article
- Biochar from fungiculture waste for adsorption of endocrine disruptors in water.Scientific reports · 2022Article
- Screen-Printed Voltammetric Sensors-Tools for Environmental Water Monitoring of Painkillers.Sensors (Basel, Switzerland) · 2022Review
- Alkyphenol Exposure Alters Steroidogenesis in Male LizardAnimals : an open access journal from MDPI · 2021Article
- Legislation against endocrine-disrupting compounds in drinking water: essential but not enough to ensure water safety.Environmental science and pollution research international · 2021Article
- Effects of a Plastic-Free Lifestyle on Urinary Bisphenol A Levels in School-Aged Children of Southern Italy: A Pilot Study.Frontiers in public health · 2021Article
- Data on occurrence and fate of emerging contaminants in a urbanised area.Data in brief · 2018Article
- Occurrence and change of estrogenic activity in the process of drinking water treatment and distribution.Environmental science and pollution research international · 2016Article
- Estimating bisphenol A exposure levels using a questionnaire targeting known sources of exposure.Public health nutrition · 2016Article
- Bisphenol A, nonylphenols, benzophenones, and benzotriazoles in soils, groundwater, surface water, sediments, and food: a review.Environmental science and pollution research international · 2015Review
- Continental bottled water assessment by stir bar sorptive extraction followed by gas chromatography-tandem mass spectrometry (SBSE-GC-MS/MS).Environmental science and pollution research international · 2014Article
- Detection of organic compounds with whole-cell bioluminescent bioassays.Advances in biochemical engineering/biotechnology · 2014Review
- Monitoring endocrine disrupting compounds and estrogenic activity in tap water from Central Spain.Environmental science and pollution research international · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated contamination by endocrine-disrupting chemicals in drinking water from 35 major Italian cities and five popular Italian brands of bottled mineral water. The quality of Italian drinking water was assessed by combing chemical analysis with bioassay to quantify specific estrogenic contaminants and to characterize the actual biological effect of the mixture of chemicals present in drinking water including the contribution of not targeted compounds. The selected contaminants were natural and synthetic steroid estrogens, alkylphenols and bisphenol A, linuron, triazine herbicides, and their metabolites. A specific analytical method was developed based on solid phase extraction of 1 L of water and concentration to 100 μL for quantification by electrospray ionization liquid chromatography tandem mass spectrometry, achieving quantification limits of 0.05-0.36 ng/L for herbicides and 0.64-7.70 ng/L for steroids and phenols. No steroid estrogens were detected in any of the samples, while bisphenol A and nonylphenols were detected in the ranges of 0.82-102.00 and 10.30-84.00 ng/L respectively. Herbicides and their degradation products, when present, were found from slightly above the quantification limits up to 49.91 ng/L, mainly from cities in northern Italy. Chemical analyses were complemented by the performance of a bioassay for the determination of the estrogenic activity in the extracts based on the transactivation of estrogen receptor α-transfected reporter HeLa-ERE-Luciferase-Neomycin cell line. Activity was generally low with maximum estrogenicity of 13.6 pg/L estradiol equivalents.
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