Evidence map›Paper›PMID 22821199›Full record

ReviewCurrent rheumatology reports2012

Reactive arthritis: developments and challenges in diagnosis and treatment.

Davina Morris, Robert D Inman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. The Case of Reactive Arthritis Secondary toCase reports in rheumatology · 2017
    Article
  8. Article
  9. [Update on reactive arthritis].Zeitschrift fur Rheumatologie · 2016
    Review
  10. Review
  11. The Etiology of Juvenile Idiopathic Arthritis.Clinical reviews in allergy & immunology · 2015
    Review
  12. Review
  13. Article
  14. Can rheumatoid arthritis be prevented?Best practice & research. Clinical rheumatology · 2013
    Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Davina MorrisToronto Western Hospital, University of Toronto, Toronto, ON, Canada.
Robert D Inman
University Health Network · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive arthritis (ReA) has traditionally been described as a nonseptic arthritis occurring in the joint following an extra-articular bacterial infection. This concept became clinically associated with antecedent infections of either the gastrointestinal or genitourinary tract. Yet this operational definition of ReA has led to diagnostic uncertainty in different clinical settings. There are several scenarios in which the ReA has been complex. One is in the SAPHO syndrome, which shares many features with ReA. Another is the development of arthritis after infection with atypical organisms such as Clostridium difficile and Giardia lamblia. Treatment of ReA remains an area of ongoing investigation. There has been a randomized controlled trial of combination antibiotics in Chlamydia-induced ReA, which reported a positive result. There are several uncontrolled reports of anti-TNF agents being used successfully in refractory ReA. These studies in treatment modalities require validation on larger samples but do provide some encouraging preliminary findings from which to develop new therapeutic approaches.

Indexed as

Acquired Hyperostosis SyndromeAnti-Bacterial AgentsArthritis, ReactiveBiological ProductsChlamydia InfectionsChlamydia trachomatisClostridioides difficileDrug Therapy, CombinationEnterocolitis, PseudomembranousGiardia lambliaGiardiasisHumansProhibitinsRandomized Controlled Trials as TopicAnti-Bacterial AgentsBiological ProductsPHB2 protein, humanProhibitins

Identifiers

PMID22821199
OpenAlexW1992866793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.