Evidence map›Paper›PMID 22820408›Full record

ReviewBrain, behavior, and immunity2013

Biobehavioral influences on recovery following hematopoietic stem cell transplantation.

Erin S Costanzo, Mark B Juckett, Christopher L Coe

Abstract readReview
In one paragraph

Review in Brain, behavior, and immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 78 citations in OpenAlex.

  1. Effects of pulmonary rehabilitation in hematopoietic stem cell transplantation recipients: a randomized controlled study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Erin S CostanzoDepartment of Psychiatry and Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53719, USA. ecostanzo@wisc.edu
Mark B Juckett
Christopher L Coe
University of Wisconsin–Madison · USUniversity of Wisconsin Carbone Cancer Center · US

Funding

Biobehavioral Mechanisms Facilitating Recovery From Stem Cell TransplantationK07CA136966 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI COSTANZO, ERIN · 2011 to 2015
$744k
Predictors of Optimal Immune Reconstitution in Stem Cell Transplant PatientsR21CA133343 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI COSTANZO, ERIN · 2010 to 2011
$350k
NCI NIH HHS K07 CA136966NCI NIH HHS R21 CA133343
6 · The paper itself

Abstract

Hematopoietic stem cell transplantation (HSCT) is a rigorous therapy that carries significant risk of morbidity and mortality to individuals with hematologic malignancies undergoing this treatment. While relationships between psychosocial factors, immune function, and clinical outcomes have been documented in other cancer populations, similar studies of cancer patients undergoing HSCT have not yet been conducted. The clinical significance of these relationships may be particularly salient in this population given the critical role of a timely immune recovery and optimal immune regulation in preventing infections, mitigating risk for graft-versus-host disease, and eliminating malignant cells, thereby reducing morbidity and mortality. Evidence for the potential role of biobehavioral processes following HSCT is reviewed, mechanisms by which psychosocial factors may influence immune processes relevant to post-transplant outcomes are discussed, and a framework to ground future psychoneuroimmunology (PNI) research in this area is provided. The review suggests that the recovery period following HSCT may provide a "window of opportunity" during which interventions targeting stress-related behavioral factors can influence the survival, health, and well-being of HSCT recipients.

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansLeukemiaLymphomaStress, Psychological

Identifiers

PMID22820408
PMCPMC3493826
OpenAlexW2134276904

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.