ArticleNature cell biology2012
Brassinosteroid, gibberellin and phytochrome impinge on a common transcription module in Arabidopsis.
Article in Nature cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 300 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
300 citing papers in PubMed, 677 citations in OpenAlex.
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- Coordinated MBW, GIS, and RSL Regulatory Networks in Plant Epidermal Patterning Under Environmental Cues.International journal of molecular sciences · 2026Review
- Genetic regulation of stem elongation and thickening in ornamental plants: a review.Horticulture research · 2026Article
- Engineering a Gibberellin-Switchable Dual-Use Line Based on Ent-Kaurene Oxidase Gene ZmKO1 Enables Two-Line Hybrid Seed Production in Maize.Plant biotechnology journal · 2026Article
- Complex Interplay of Tandem, Segmental, Whole Genome Duplication, and Re-organization Drives Expansion of SAUR Gene Family in Brassicaceae.Biochemical genetics · 2026Article
- Silicon mitigates combined cadmium and microplastics toxicity in rice by regulating glyoxalase system, and phytochelatin-mediated cadmium detoxification.BMC plant biology · 2026Article
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- Integrative molecular mechanisms of lodging resistance in rice (Frontiers in plant science · 2026Review
- ROS-mediated interplay between brassinosteroids and gibberellic acids antagonistically modulates asymmetric periclinal cell division leading to middle cortex formation inPlant signaling & behavior · 2025Article
- Brassinosteroids promote sugar synthesis by inhibiting BIN2 phosphorylation of phosphoenolpyruvate carboxykinase.bioRxiv : the preprint server for biology · 2025Article
- The transcriptome analysis reveals the regulatory mechanisms of female sterility in Lagerstroemia speciosa 'Zichan'.BMC plant biology · 2025Article
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- Gibberellin transport affects lateral root growth through HY5 in response to far-red light.The Plant cell · 2025Article
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- The 14-3-3 Protein OsGF14h Coordinates Brassinosteroid and Gibberellin Signaling to Regulate Plant Growth and Grain Yield in Rice.Rice (New York, N.Y.) · 2025Article
- Elucidating the role of brassinosteroid signaling genes and their promoters in Arabidopsis revealed regulatory mechanisms in plant development and responses to different abiotic stresses.BMC plant biology · 2025Article
240 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Brassinosteroid and gibberellin promote many similar developmental responses in plants; however, their relationship remains unclear. Here we show that BR and GA act interdependently through a direct interaction between the BR-activated BZR1 and GA-inactivated DELLA transcription regulators. GA promotion of cell elongation required BR signalling, whereas BR or active BZR1 suppressed the GA-deficient dwarf phenotype. DELLAs directly interacted with BZR1 and inhibited BZR1-DNA binding both in vitro and in vivo. Genome-wide analysis defined a BZR1-dependent GA-regulated transcriptome, which is enriched with light-regulated genes and genes involved in cell wall synthesis and photosynthesis/chloroplast function. GA promotion of hypocotyl elongation requires both BZR1 and the phytochrome-interacting factors (PIFs), as well as their common downstream targets encoding the PRE-family helix-loop-helix factors. The results demonstrate that GA releases DELLA-mediated inhibition of BZR1, and that the DELLA-BZR1-PIF4 interaction defines a core transcription module that mediates coordinated growth regulation by GA, BR and light signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.