ArticleApplied and environmental microbiology2012
Isolated microbial single cells and resulting micropopulations grow faster in controlled environments.
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Microfluidic Single-Cell Analytics.Advances in biochemical engineering/biotechnology · 2022Article
- Segregostat: a novel concept to control phenotypic diversification dynamics on the example of Gram-negative bacteria.Microbial biotechnology · 2019Article
- In Silico Prediction of Large-Scale Microbial Production Performance: Constraints for Getting Proper Data-Driven Models.Computational and structural biotechnology journal · 2018Review
- Beyond the bulk: disclosing the life of single microbial cells.FEMS microbiology reviews · 2017Review
- Bioprocess scale-up/down as integrative enabling technology: from fluid mechanics to systems biology and beyond.Microbial biotechnology · 2017Article
- From Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality.Frontiers in microbiology · 2017Review
- Label-free isolation and deposition of single bacterial cells from heterogeneous samples for clonal culturing.Scientific reports · 2016Article
- Advancing microbial sciences by individual-based modelling.Nature reviews. Microbiology · 2016Review
- Review of methods to probe single cell metabolism and bioenergetics.Metabolic engineering · 2015Review
- Colonial vs. planktonic type of growth: mathematical modeling of microbial dynamics on surfaces and in liquid, semi-liquid and solid foods.Frontiers in microbiology · 2015Review
- Challenging biological limits with microfluidic single cell analysis.Microbial biotechnology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Singularized cells of Pichia pastoris, Hansenula polymorpha, and Corynebacterium glutamicum displayed specific growth rates under chemically and physically constant conditions that were consistently higher than those obtained in populations. This highlights the importance of single-cell analyses by uncoupling physiology and the extracellular environment, which is now possible using the Envirostat 2.0 concept.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.