ArticleCerebral cortex (New York, N.Y. : 1991)2013
Resting-state synchrony during early alcohol abstinence can predict subsequent relapse.
Article in Cerebral cortex (New York, N.Y. : 1991), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 76 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Combining Neuro-Imaging and Non-Invasive Brain Stimulation for Clinical Intervention in Alcohol Use Disorder
Neuromodulation and Cognitive Training in Opioid Use Disorder
Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.
- Anxiety during abstinence from alcohol: A systematic review of rodent and human evidence for the anterior insula's role in the abstinence network.Addiction biology · 2021Pooled it
- Repetitive deep TMS in alcohol dependent patients halts progression of white matter changes in early abstinence.Psychiatry and clinical neurosciences · 2024Trial
- Sex differences in tobacco smokers: Executive control network and frontostriatal connectivity.Drug and alcohol dependence · 2019Trial
- From the neurobiological basis of comorbid alcohol dependence and depression to psychological treatment strategies: study protocol of a randomized controlled trial.BMC psychiatry · 2017Trial
- An eight month randomized controlled exercise intervention alters resting state synchrony in overweight children.Neuroscience · 2014Trial
- Frontal tDCS reduces alcohol relapse rates by increasing connections from left dorsolateral prefrontal cortex to addiction networks.Brain stimulationTrial
- MRI assessment of intrinsic neural timescales in male alcohol use disorder patients.Frontiers in psychiatry · 2026Article
- Repeated alcohol drinking in mice is associated with bidirectional alterations in corticostriatal coherence.Neuropharmacology · 2025Article
- Altered effective connectivity of emotion perception and regulation networks during an emotional face perception task in adults with alcohol use disorder.Brain structure & function · 2025Article
- Effects of alcohol and cannabis co-use on salience network resting state functional connectivity in individuals who drink alcohol heavily.Drug and alcohol dependence · 2025Article
- The effect of chronic stress and chronic alcohol intake on behaviour, brain volume, and functional connectivity in a longitudinal rat model.Brain communications · 2025Article
- Aberrant regional homogeneity in multiple frequency bands in patients with alcohol use disorder.Frontiers in psychiatry · 2025Article
- Smoking Progression and Nicotine-Enhanced Reward Sensitivity Predicted by Resting-State Functional Connectivity in Salience and Executive Control Networks.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Observational
- Bed nucleus of the stria terminalis network responses to unpredictable threat in early alcohol abstinence.Alcohol, clinical & experimental research · 2024Article
- Alterations of brain activity in patients with alcohol use disorder: a resting-state fMRI study.BMC psychiatry · 2023Article
- Transcranial Magnetic Stimulation as a Tool to Promote Smoking Cessation and Decrease Drug and Alcohol Use.Brain sciences · 2023Review
- Reduced connectivity of the cognitive control neural network at rest in young adults who had their first drink of alcohol prior to age 18.Psychiatry research. Neuroimaging · 2023Article
- Alterations in BNST Intrinsic Functional Connectivity in Early Abstinence from Alcohol Use Disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2023Article
- Federated Analysis in COINSTAC Reveals Functional Network Connectivity and Spectral Links to Smoking and Alcohol Consumption in Nearly 2,000 Adolescent Brains.Neuroinformatics · 2023Article
- Value-based decision-making network functional connectivity correlates with substance use and delay discounting behaviour among young adults.NeuroImage. Clinical · 2023Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Short-term abstinent alcoholics have shown increased engagement of reward regions and reduced engagement of executive control regions. There is no report yet on whether these differences can predict relapse. This is the first study that investigates whether differences in resting-state networks can predict later relapse. Resting-state functional magnetic resonance imaging data were collected from 69 short-term abstinent alcoholics. Participants performed the affective go/no-go task outside of the scanner. At 6-month follow-up, participants were grouped as abstainers (N = 40; age: M = 46.70, standard deviation [SD] = 6.83) and relapsers (N = 29; age: M = 46.91, SD = 7.25). We examined baseline resting-state synchrony (RSS) using seed-based measures. Compared with abstainers, relapsers showed significantly decreased RSS within both the reward and executive control networks as well as within the visual network (P < 0.05). Lower RSS in relapsers could predict relapse (P < 0.05) and was significantly correlated with poor inhibitory control of emotional-laden stimuli (P < 0.017) and with alcohol use (P < 0.05). Results suggest that lower RSS during short-term abstinence may predict subsequent relapse. The association of lower RSS with poorer inhibitory control suggests that low RSS may constitute a faulty foundation for future responses to external cues, which can be manifested as the inability to inhibit behavior.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.