Evidence map›Paper›PMID 22817979›Full record

ArticleJournal of the International Society of Sports Nutrition2012

Creatine supplementation with specific view to exercise/sports performance: an update.

Robert Cooper, Fernando Naclerio, Judith Allgrove, Alfonso Jimenez

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the International Society of Sports Nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07233707 (Impact of Creatine Monohydrate Supplementation on Breath-Hold Exercise Performance on a Bicycle Ergometer), which is not on this map. Cited by 109 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 13 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07233707 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Impact of Creatine Monohydrate Supplementation on Breath-Hold Exercise Performance on a Bicycle Ergometer

TypeinterventionalSponsorHarokopio UniversityRan2025 to 2026Enrolled26ConditionsHealthyArmsCreatine Monohydrate, Placebo Control
3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 13 syntheses or guidelines pooled it, 297 citations in OpenAlex.

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  4. Sport supplementation in competitive swimmers: a systematic review with meta-analysis.Journal of the International Society of Sports Nutrition · 2025
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Robert CooperCentre for Sports Science and Human Performance, School of Science, University of Greenwich at Medway, Central Avenue, Chatham Maritime, Kent, ME4 4TB, United Kingdom. cr86@gre.ac.uk.
Fernando Naclerio
Judith Allgrove
Alfonso Jimenez
Centre For Human Genetics · INEnglish Institute of Sport · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Creatine is one of the most popular and widely researched natural supplements. The majority of studies have focused on the effects of creatine monohydrate on performance and health; however, many other forms of creatine exist and are commercially available in the sports nutrition/supplement market. Regardless of the form, supplementation with creatine has regularly shown to increase strength, fat free mass, and muscle morphology with concurrent heavy resistance training more than resistance training alone. Creatine may be of benefit in other modes of exercise such as high-intensity sprints or endurance training. However, it appears that the effects of creatine diminish as the length of time spent exercising increases. Even though not all individuals respond similarly to creatine supplementation, it is generally accepted that its supplementation increases creatine storage and promotes a faster regeneration of adenosine triphosphate between high intensity exercises. These improved outcomes will increase performance and promote greater training adaptations. More recent research suggests that creatine supplementation in amounts of 0.1 g/kg of body weight combined with resistance training improves training adaptations at a cellular and sub-cellular level. Finally, although presently ingesting creatine as an oral supplement is considered safe and ethical, the perception of safety cannot be guaranteed, especially when administered for long period of time to different populations (athletes, sedentary, patient, active, young or elderly).

Identifiers

PMID22817979
PMCPMC3407788
OpenAlexW2110199151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.