ArticleGastrointestinal endoscopy2012
Endoscopic sclerotherapy for the treatment of weight regain after Roux-en-Y gastric bypass: outcomes, complications, and predictors of response in 575 procedures.
Article in Gastrointestinal endoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- The use of endoluminal techniques in the revision of primary bariatric surgery procedures: a systematic review.Surgical endoscopy · 2020Pooled it
- Revision of Roux-En-Y Gastric Bypass for Weight Regain: a Systematic Review of Techniques and Outcomes.Obesity surgery · 2016Pooled it
- Influence of the argon plasma coagulation protocol in endoscopic procedures on body composition in patients with recurrent weight gain after Roux-en-Y gastric bypass: a randomized clinical trial.Surgical endoscopy · 2026Trial
- Endoluminal Revision (OverStitch (TM) , Apollo Endosurgery) of the Dilated Gastroenterostomy in Patients with Late Dumping Syndrome After Proximal Roux-en-Y Gastric Bypass.Obesity surgery · 2016Trial
- Argon plasma coagulation of gastrojejunal anastomosis for weight regain after gastric bypass.Obesity surgery · 2015Trial
- Efficacy of the argon plasma coagulation in patients with weight regain after gastric bypass: a randomized control trial.Endoscopy international open · 2023Article
- Endoscopic therapy of weight regain after bariatric surgery.World journal of gastrointestinal surgery · 2021Review
- The Mitigating Effect of Phentermine and Topiramate on Weight Regain After Roux-en-Y Gastric Bypass Surgery.Obesity (Silver Spring, Md.) · 2020Article
- Photosensitizers Used in the Photodynamic Therapy of Rheumatoid Arthritis.International journal of molecular sciences · 2019Review
- Endoscopic Gastrojejunal Revisions Following Gastric Bypass: Lessons Learned in More Than 100 Consecutive Patients.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
- Development of Bariatric and Metabolic Endoscopy.Chinese medical journal · 2018Review
- Endoscopic Evaluation/Management of Bariatric Surgery Complications.Current treatment options in gastroenterology · 2017Review
- Complications of Bariatric Surgery: What You Can Expect to See in Your GI Practice.The American journal of gastroenterology · 2017Review
- The utility of weight loss medications after bariatric surgery for weight regain or inadequate weight loss: A multi-center study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017Article
- Weight regain after Roux-en-Y gastric bypass has a large negative impact on the Bariatric Quality of Life Index.BMJ open gastroenterology · 2017Article
- Endoscopic Approach for Major Complications of Bariatric Surgery.Clinical endoscopy · 2017Article
- Gastrojejunal anastomotic reduction for weight regain in roux-en-y gastric bypass patients: physiological, behavioral, and anatomical effects of endoscopic suturing and sclerotherapy.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2016Article
- New endoscopic procedures for diabetes mellitus type 2 and obesity treatment.Gland surgery · 2016Article
- Weight loss endoscopy: Development, applications, and current status.World journal of gastroenterology · 2016Review
- Endoscopic Devices for Obesity.Current obesity reports · 2016Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWeight regain after Roux-en-Y gastric bypass (RYGB) is common. Endoscopic sclerotherapy is increasingly used to treat this weight regain.
objectivesTo report safety, outcomes, durability, and predictors of response to sclerotherapy in a large prospective cohort.
designRetrospective analysis of a prospective cohort study of patients with weight regain after RYGB. PATIENTS: A total of 231 consecutive patients undergoing 575 sclerotherapy procedures between September 2008 and March 2011.
interventionsSingle or multiple sclerotherapy procedures to inject sodium morrhuate into the rim of the gastrojejunal anastomosis. MAIN OUTCOME MEASUREMENTS: We report weight loss, complications, and predictors of response. We also used Kaplan-Meier survival analysis and log-rank test to compare time to continuation of weight regain after sclerotherapy in patients undergoing a single versus multiple sclerotherapy procedures.
resultsAt 6 and 12 months from the last sclerotherapy procedure, weight regain stabilized in 92% and 78% of the cohort, respectively. Those who underwent 2 or 3 sclerotherapy sessions had significantly higher rates of weight regain stabilization than those who underwent a single session (90% vs 60% at 12 months; P = .003). The average weight loss at 6 months from the last sclerotherapy session for the entire cohort was 10 lb (standard deviation 16), representing 18% of the weight regained after RYGB. A subset of 73 patients (32% of the cohort) had greater weight loss at 6 months (26 lb, standard deviation 12), representing 61% of the weight regained. Predictors of a favorable outcome included greater weight regain and the number of sclerotherapy procedures. Bleeding was reported in 2.4% of procedures and transient diastolic blood pressure increases in 15%, without adverse health outcomes. No GI perforations were reported.
conclusionsEndoscopic sclerotherapy appears to be a safe and effective tool for the management of weight regain after RYGB.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.