ArticleAlcoholism, clinical and experimental research2013
Prenatal alcohol exposure, attention-deficit/hyperactivity disorder, and sluggish cognitive tempo.
Article in Alcoholism, clinical and experimental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prenatal alcohol exposure and associations with physical size, dysmorphology and neurodevelopment: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Cognitive disengagement syndrome (sluggish cognitive tempo) and medical conditions: a systematic review and call for future research.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2024Pooled it
- Prenatal alcohol exposure and offspring mental health: A systematic review.Drug and alcohol dependence · 2019Pooled it
- Optimal Items for Assessing Sluggish Cognitive Tempo in Children Across Mother, Father, and Teacher Ratings.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Pooled it
- Nicotine metabolites generate craniofacial defects that are worsened by ethanol exposure.PNAS nexus · 2026Article
- Persistent Alterations of Brain and Behavior in Children With Low Prenatal Alcohol Exposure.Biological psychiatry global open science · 2026Article
- Examining ADHD and Cognitive Disengagement Syndrome Symptoms in Relation to Food Insecurity in Early Adolescents.Research on child and adolescent psychopathology · 2024Article
- Setting a research agenda for examining early risk for elevated cognitive disengagement syndrome symptoms using data from the ABCD cohort.Research square · 2024Article
- Cognitive disengagement syndrome in pediatric patients with long COVID: associations with mood, anxiety, and functional impairment.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2024Article
- Cognitive disengagement syndrome in pediatric spina bifida.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2024Article
- Report of a Work Group on Sluggish Cognitive Tempo: Key Research Directions and a Consensus Change in Terminology to Cognitive Disengagement Syndrome.Journal of the American Academy of Child and Adolescent Psychiatry · 2023Article
- Prenatal exposure to alcohol impairs responses of cerebral arterioles to activation of potassium channels: Role of oxidative stress.Alcohol, clinical & experimental research · 2023Article
- Binge-like Prenatal Ethanol Exposure Causes Impaired Cellular Differentiation in the Embryonic Forebrain and Synaptic and Behavioral Defects in Adult Mice.Brain sciences · 2022Article
- Postnatal Ethanol Exposure Activates HDAC-Mediated Histone Deacetylation, Impairs Synaptic Plasticity Gene Expression and Behavior in Mice.The international journal of neuropsychopharmacology · 2020Article
- Clinical correlates of sluggish cognitive tempo in adolescents with autism spectrum disorder.Autism : the international journal of research and practice · 2019Article
- The Influence of Extrinsic Reinforcement on Children with Heavy Prenatal Alcohol Exposure.Alcoholism, clinical and experimental research · 2016Article
- An fMRI study of behavioral response inhibition in adolescents with and without histories of heavy prenatal alcohol exposure.Behavioural brain research · 2015Article
- Impaired ILK Function Is Associated with Deficits in Hippocampal Based Memory and Synaptic Plasticity in a FASD Rat Model.PloS one · 2015Article
- The clinical utility and specificity of parent report of executive function among children with prenatal alcohol exposure.Journal of the International Neuropsychological Society : JINS · 2014Article
- Effects of prenatal alcohol exposure and attention-deficit/hyperactivity disorder on adaptive functioning.Alcoholism, clinical and experimental research · 2014Article
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13 authors.
Funding
Abstract
backgroundChildren with heavy prenatal alcohol exposure often meet criteria for attention-deficit/hyperactivity disorder (ADHD). ADHD research has examined subtype differences in symptomatology, including sluggish cognitive tempo (SCT). This construct is defined by behavioral symptoms including hypoactivity and daydreaming and has been linked to increased internalizing behaviors. The current study examined whether similar findings are displayed in children with prenatal alcohol exposure.
methodsAs part of a multisite study, caregivers of 272 children (8 to 16 years) completed the SCT Scale and Child Behavior Checklist (CBCL). Four groups were included: alcohol-exposed children with ADHD (ALC+; n = 75), alcohol-exposed children without ADHD (ALC-; n = 35), nonexposed children with ADHD (ADHD; n = 60), and nonexposed children without ADHD (CON; n = 102). SCT and CBCL scores were analyzed using 2 (exposure) × 2 (ADHD) analyses of variance. Pearson's correlations measured the relationships between SCT, CBCL, and Full Scale IQ (FSIQ). Discriminant function analysis examined whether SCT items could accurately classify groups.
resultsAnalyses revealed significant main effects of exposure and ADHD on SCT and internalizing and externalizing scores and significant interaction effects on SCT and internalizing scores. SCT significantly correlated with internalizing, externalizing, and attention ratings in all groups and with FSIQ in ALC+. Discriminant function analysis indicated that specific SCT items could distinguish ALC- from CON.
conclusionsAlcohol-exposed children exhibited elevated SCT scores. Elevations were related to increased parent ratings of internalizing and externalizing behaviors and attention. These findings are observed in alcohol-exposed children regardless of ADHD symptoms and specific SCT items proved useful in distinguishing exposed children, suggesting clinical utility for this measure in further defining the neurobehavioral profile related to prenatal alcohol exposure.
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