ArticleBMC genomics2012
Composition and organization of active centromere sequences in complex genomes.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Diploid dual assemblies reveal the telocentric structure and extensive allelic heterogeneity of canine genomes.NAR genomics and bioinformatics · 2026Article
- Identification and characterization of centromeric sequences inGenome research · 2021Article
- A novel canine reference genome resolves genomic architecture and uncovers transcript complexity.Communications biology · 2021Article
- Conservation, Divergence, and Functions of Centromeric Satellite DNA Families in the Bovidae.Genome biology and evolution · 2019Article
- Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer.Molecular cell · 2018Article
- Rapid molecular assays to study human centromere genomics.Genome research · 2017Article
- The first draft reference genome of the American mink (Neovison vison).Scientific reports · 2017Article
- Expressed Centromere Specific Histone 3 (Frontiers in plant science · 2017Article
- Structure of the germline genome ofeLife · 2016Article
- Genome-wide analysis of tandem repeats in Tribolium castaneum genome reveals abundant and highly dynamic tandem repeat families with satellite DNA features in euchromatic chromosomal arms.DNA research : an international journal for rapid publication of reports on genes and genomes · 2015Article
- Centromere identity from the DNA point of view.Chromosoma · 2014Review
- Genomic characterization of large heterochromatic gaps in the human genome assembly.PLoS computational biology · 2014Article
- Distinct chromatin features characterize different classes of repeat sequences in Drosophila melanogaster.BMC genomics · 2014Article
- Sex specific expression and distribution of small RNAs in papaya.BMC genomics · 2014Article
- Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution.Genome biology · 2013Article
- High-resolution mapping and transcriptional activity analysis of chicken centromere sequences on giant lampbrush chromosomes.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCentromeres are sites of chromosomal spindle attachment during mitosis and meiosis. While the sequence basis for centromere identity remains a subject of considerable debate, one approach is to examine the genomic organization at these active sites that are correlated with epigenetic marks of centromere function.
resultsWe have developed an approach to characterize both satellite and non-satellite centromeric sequences that are missing from current assemblies in complex genomes, using the dog genome as an example. Combining this genomic reference with an epigenetic dataset corresponding to sequences associated with the histone H3 variant centromere protein A (CENP-A), we identify active satellite sequence domains that appear to be both functionally and spatially distinct within the overall definition of satellite families.
conclusionsThese findings establish a genomic and epigenetic foundation for exploring the functional role of centromeric sequences in the previously sequenced dog genome and provide a model for similar studies within the context of less-characterized genomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.