ArticleNatural product communications2012
Two antiproliferative saponins of Tarenna grevei from the Madagascar dry forest [1].
Article in Natural product communications, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Amyloid β aggregation inhibitory activity of triterpene saponins from the cactus Stenocereus pruinosus.Journal of natural medicines · 2021Article
- Neuroprotective effects of vomifoliol, isolated from3 Biotech · 2020Article
- Triterpenoid saponins from Polaskia chichipe Backbg. and their inhibitory or promotional effects on the melanogenesis of B16 melanoma cells.Journal of natural medicines · 2017Article
- Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber.Reports of biochemistry & molecular biology · 2014Article
- Two antiproliferative triterpene saponins from Nematostylis anthophylla from the highlands of Central Madagascar.Chemistry & biodiversity · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Antiproliferative bioassay-guided fractionation of the ethanol extract of the endemic Malagasy Rubiaceous plant Tarenna grevei led to the isolation of two new antiproliferative oxygenated oleanane triterpene saponins. The structures of the two active compounds were elucidated as 23-hydroxylongispinogenin 3-O-beta-D-glucopyranoside (1) and longispinogenin 3-O-beta-D-glucopyranosyl (1 --> 2)-beta-D-glucopyranoside (3) by analyses of their spectral data including 1D- and 2D-NMR spectroscopy and chemical evidence. Compounds 1 and 3 displayed moderate antiproliferative activity against the A2780 ovarian cancer cell line with IC50 values of 7.6 and 4 microM, respectively.
Indexed as
Identifiers
22816288PMC3480188What OpenQuestion holds
Registered trials
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