Evidence map›Paper›PMID 22816134›Full record

ReviewTherapeutic delivery2010

Advances in image-guided intratumoral drug delivery techniques.

Luis Solorio, Ravi B Patel, Hanping Wu, Tianyi Krupka, Agata A Exner

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Modified gefitinib conjugated FeFrontiers in bioengineering and biotechnology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Electrospray for generation of drug delivery and vaccine particles applied in vitro and in vivo.Materials science & engineering. C, Materials for biological applications · 2019
    Review
  10. Article
  11. Article
  12. Image-guided thermal therapy with a dual-contrast magnetic nanoparticle formulation: A feasibility study.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2016
    Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luis SolorioCase Western Reserve University, S1100 Euclid Ave., Cleveland, OH 44106, USA.
Ravi B Patel
Hanping Wu
Tianyi Krupka
Agata A Exner

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
Clinical and Translational Science Collaborative of ClevelandKL2TR000440 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$11.1M
NCATS NIH HHS KL2 TR000440NCATS NIH HHS UL1 TR000439NIGMS NIH HHS T32 GM007250
6 · The paper itself

Abstract

Image-guided drug delivery provides a means for treating a variety of diseases with minimal systemic involvement while concurrently monitoring treatment efficacy. These therapies are particularly useful to the field of interventional oncology, where elevation of tumor drug levels, reduction of systemic side effects and post-therapy assessment are essential. This review highlights three such image-guided procedures: transarterial chemoembolization, drug-eluting implants and convection-enhanced delivery. Advancements in medical imaging technology have resulted in a growing number of new applications, including image-guided drug delivery. This minimally invasive approach provides a comprehensive answer to many challenges with local drug delivery. Future evolution of imaging devices, image-acquisition techniques and multifunctional delivery agents will lead to a paradigm shift in patient care.

Indexed as

Chemoembolization, TherapeuticDiagnostic ImagingDrug Delivery SystemsDrug ImplantsAnimalsAntineoplastic AgentsBiological AvailabilityBiological TransportChemistry, PharmaceuticalConvectionDrug CarriersDrug CompoundingHumansNeoplasmsTechnology, PharmaceuticalAntineoplastic AgentsDrug CarriersDrug Implants

Identifiers

PMID22816134
PMCPMC5568554

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.