Evidence map›Paper›PMID 22815919›Full record

ArticlePloS one2012

Predictive sequence analysis of the Candidatus Liberibacter asiaticus proteome.

Qian Cong, Lisa N Kinch, Bong-Hyun Kim, Nick V Grishin

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Time-Course Gene Expression of 'Microorganisms · 2025
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  4. A serralysin-like protein ofFrontiers in microbiology · 2022
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  8. The Ferredoxin-Like Protein FerR Regulates PrbP Activity inApplied and environmental microbiology · 2019
    Article
  9. Review
  10. Article
  11. Article
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  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Qian CongDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Lisa N Kinch
Bong-Hyun Kim
Nick V Grishin
The University of Texas Southwestern Medical Center · USHoward Hughes Medical Institute · US

Funding

Computational methods for structural-functional studies of proteinsR01GM094575 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI GRISHIN, NICK V. · 2010 to 2017
$2.4M
Howard Hughes Medical InstituteNIGMS NIH HHS GM094575NIGMS NIH HHS R01 GM094575
6 · The paper itself

Abstract

Candidatus Liberibacter asiaticus (Ca. L. asiaticus) is a parasitic gram-negative bacterium that is closely associated with Huanglongbing (HLB), a worldwide citrus disease. Given the difficulty in culturing the bacterium and thus in its experimental characterization, computational analyses of the whole Ca. L. asiaticus proteome can provide much needed insights into the mechanisms of the disease and guide the development of treatment strategies. In this study, we applied state-of-the-art sequence analysis tools to every Ca. L. asiaticus protein. Our results are available as a public website at http://prodata.swmed.edu/liberibacter_asiaticus/. In particular, we manually curated the results to predict the subcellular localization, spatial structure and function of all Ca. L. asiaticus proteins (http://prodata.swmed.edu/liberibacter_asiaticus/curated/). This extensive information should facilitate the study of Ca. L. asiaticus proteome function and its relationship to disease. Pilot studies based on the information from our website have revealed several potential virulence factors, discussed herein.

Indexed as

AlphaproteobacteriaAmino Acid MotifsAmino Acid SequenceDatabases, FactualGenome, BacterialGram-Negative BacteriaModels, MolecularMolecular ConformationMolecular Sequence DataPilot ProjectsPlantsProtein ConformationProteomeProteomicsSequence Homology, Amino AcidVirulence FactorsProteomeVirulence Factors

Identifiers

PMID22815919
PMCPMC3399792
OpenAlexW1970477595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.