ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Robustness of a rhythmic circuit to short- and long-term temperature changes.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed.
- Compensation of the effects of temperature on a motor system in the crab,bioRxiv : the preprint server for biology · 2026Article
- Temperature and pH-dependent potassium currents of muscles of the stomatogastric nervous system of the crab,iScience · 2026Article
- Neural temporal scaling accounts for robust hunting behavior across temperatures.Nature communications · 2026Article
- The combined effects of temperature and salinity on the stomatogastric nervous system of two species of decapod crustacea.Journal of neurophysiology · 2026Article
- Rhythm generation, robustness, and control in stick insect locomotion: modeling and analysis.Journal of computational neuroscience · 2025Article
- Temperature and pH-dependent Potassium Currents of Muscles of the Stomatogastric Nervous System of the Crab,bioRxiv : the preprint server for biology · 2025Article
- Decoding thermal resilience in fish: acute warming tolerance is associated with neural failure in rainbow trout.Biology letters · 2025Article
- Homeostatic regulation of a motor circuit through temperature sensing rather than activity sensing.Current biology : CB · 2025Article
- Imperatives and co-benefits of research into climate change and neurological disease.Nature reviews. Neurology · 2025Review
- Increased robustness and adaptation to simultaneous temperature and elevated extracellular potassium in the pyloric rhythm of the crab,Journal of neurophysiology · 2025Article
- Neural Processing without OPhysiology (Bethesda, Md.) · 2024Review
- Alterations in network robustness upon simultaneous temperature and pH perturbations.Journal of neurophysiology · 2024Article
- Modulation by Neuropeptides with Overlapping Targets Results in Functional Overlap in Oscillatory Circuit Activation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- A biophysical perspective on the resilience of neuronal excitability across timescales.Nature reviews. Neuroscience · 2023Review
- Intrinsic neural diversity quenches the dynamic volatility of neural networks.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Thermal acclimation and habitat-dependent differences in temperature robustness of a crustacean motor circuit.Frontiers in cellular neuroscience · 2023Article
- The role of feedback and modulation in determining temperature resiliency in the lobster cardiac nervous system.Frontiers in neuroscience · 2023Article
- Oscillatory network spontaneously recovers both activity and robustness after prolonged removal of neuromodulators.Frontiers in cellular neuroscience · 2023Article
- Energy-efficient network activity from disparate circuit parameters.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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4 authors.
Funding
Abstract
Recent computational and experimental work has shown that similar network performance can result from variable sets of synaptic and intrinsic properties. Because temperature is a global perturbation that differentially influences every biological process within the nervous system, one might therefore expect that individual animals would respond differently to temperature. Nonetheless, the phase relationships of the pyloric rhythm of the stomatogastric ganglion (STG) of the crab, Cancer borealis, are remarkably invariant between 7 and 23°C (Tang et al., 2010). Here, we report that, when isolated STG preparations were exposed to more extreme temperature ranges, their networks became nonrhythmic, or "crashed", in a reversible fashion. Animals were acclimated for at least 3 weeks at 7, 11, or 19°C. When networks from the acclimated animals were perturbed by acute physiologically relevant temperature ramps (11-23°C), the network frequency and phase relationships were independent of the acclimation group. At high acute temperatures (>23°C), circuits from the cold-acclimated animals produced less-regular pyloric rhythms than those from warm-acclimated animals. At high acute temperatures, phase relationships between pyloric neurons were more variable from animal to animal than at moderate acute temperatures, suggesting that individual differences across animals in intrinsic circuit parameters are revealed at high temperatures. This shows that individual and variable neuronal circuits can behave similarly in normal conditions, but their behavior may diverge when confronted with extreme external perturbations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.