Evidence map›Paper›PMID 22814894›Full record

ArticleLasers in medical science2013

Effects of low-intensity laser therapy on periodontal tissue remodeling during relapse and retention of orthodontically moved teeth.

Su-Jung Kim, Yoon-Goo Kang, Jong-Hyun Park, Eun-Cheol Kim, Young-Guk Park

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05723094 (Effect of Low-Level Laser Therapy on Stability During Retention Phase After Orthodontic Treatment), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05723094 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effect of Low-Level Laser Therapy on Stability During Retention Phase After Orthodontic Treatment: A Randomized Controlled Trial.

TypeinterventionalSponsorUniversiti Sains MalaysiaRan2022 to 2023Enrolled32ConditionsOrthodontic Retainers, Laser TherapyArmsGa-Al-As diode laser (Ilase, USA), placebo
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Su-Jung KimDepartment of Orthodontics, Oral Biology Research Institute, Kyung Hee University School of Dentistry, 1 Hoegi-dong, Dongdaemoon-Ku, Seoul, 130-701, Korea.
Yoon-Goo Kang
Jong-Hyun Park
Eun-Cheol Kim
Young-Guk Park
Kyung Hee University · KRKyung Hee University Dental Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was designed to investigate the effects of low-intensity laser therapy (LILT) on periodontal ligament (PDL) remodeling during relapse and retention after the completion of orthodontic movement. The maxillary central incisors (n = 104) of the 52 rats were randomly divided into five groups according to the treatment modality: baseline control group without any intervention (n = 8); relapse group without retainer after tooth movement (n = 24); retention group with fixed retainer after tooth movement (n = 24); lased relapse group without retainer after tooth movement and LILT (n = 24); lased retention group with retainer after tooth movement and LILT (n = 24). LILT was daily performed using a gallium-aluminum-arsenide diode laser in a biostimulation mode: wavelength of 780 nm, continuous waves at 70 mW output power, a preset low intensity of 1.75 W/cm(2) in contact mode, resulting in energy dose of 5 J/cm(2) per irradiation for 3 s. The animals were euthanized on days 1, 3, and 7 after removal of the orthodontic appliance. Real-time RT-PCR was performed for quantitative analysis of matrix metalloproteinases mRNA expression. Immunoreactivities of collagen and tissue inhibitor of metalloproteinase were observed on the compression and tension sides. LILT significantly facilitated the expression of five tested MMP mRNAs in both relapse and retention groups. TIMP-1 immunoreactivity was inhibited by LILT in both groups, whereas Col-I immunoreactivity was increased by LILT only in the retention group. These results indicate that LILT would act differently on the stability after orthodontic treatment according to additional retainer wearing or not. LILT when combined with a retainer on the moved teeth may shorten the retention period by accelerating periodontal remodeling in the new tooth position, whereas, LILT on the moved teeth left without any retainer would rather increase the rate of relapse after treatment.

Indexed as

Tooth Movement TechniquesAnalysis of VarianceAnimalsGene ExpressionImmunoenzyme TechniquesLasers, SemiconductorLow-Level Light TherapyMatrix MetalloproteinasesPeriodontal LigamentPhotomicrographyRandom AllocationRatsRats, Sprague-DawleyReal-Time Polymerase Chain ReactionRecurrenceStatistics, NonparametricMatrix Metalloproteinases

Identifiers

PMID22814894
OpenAlexW2045603597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.