SynthesisBreast cancer research and treatment2012
Physical activity and mammographic breast density: a systematic review.
Synthesis in Breast cancer research and treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Dietary Patterns, Dietary Interventions, and Mammographic Breast Density: A Systematic Literature Review.Nutrients · 2022Pooled it
- Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide.PLoS medicine · 2017Pooled it
- Trace element imbalances in selenium and mercury in relation to mammographic density and breast cancer progression: a case‒control study.Scientific reports · 2025Article
- Physical Activity and Mammographic Density in Japanese Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Cigarette smoking and mammographic breast density in post-menopausal women from the EPIC Florence cohort.Frontiers in oncology · 2024Article
- The FEDRA Longitudinal Study: Repeated Volumetric Breast Density Measures and Breast Cancer Risk.Cancers · 2023Article
- Association Between Lifestyle Changes, Mammographic Breast Density, and Breast Cancer.The oncologist · 2022Review
- The epidemiologic factors associated with breast density: A review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Review
- Regular physical activity and mammographic density: a cohort study.Cancer causes & control : CCC · 2018Article
- The metabolic syndrome and mammographic breast density in a racially diverse and predominantly immigrant sample of women.Cancer causes & control : CCC · 2015Article
- The interaction between early-life body size and physical activity on risk of breast cancer.International journal of cancer · 2015Article
- Background risk of breast cancer and the association between physical activity and mammographic density.Breast cancer research : BCR · 2015Article
- Association between the Adherence to the International Guidelines for Cancer Prevention and Mammographic Density.PloS one · 2015Article
- Adolescent physical activity and inactivity: a prospective study of risk of benign breast disease in young women.Breast cancer research and treatment · 2014Article
- The Influence of Energetic Factors on Biomarkers of Postmenopausal Breast Cancer Risk.Current nutrition reports · 2014Review
- Adolescent and young adult exposure to physical activity and breast density.Medicine and science in sports and exercise · 2013Article
- Invited commentary: are dietary intakes and other exposures in childhood and adolescence important for adult cancers?American journal of epidemiology · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Studies show a protective relationship between physical activity and breast cancer risk across the life course from menarche to postmenopausal years. Mammographic breast density is a known and strong breast cancer risk factor. Whether the association of physical activity with breast cancer risk is mediated through mammographic breast density is poorly understood. This systematic review summarizes published studies that investigated the association between physical activity and mammographic breast density and discusses the methodological issues that need to be addressed. We included in this review studies that were published before October 31, 2011 that were accessible in full-text format and were published in English. We identified 20 studies through the PubMed Central, BioMed Central, Embase, and Scopus and using the search terms "physical activity and breast density" and "exercise and breast density" as well as through manual searches of the bibliographies of the articles identified in electronic searches. We found no evidence of association between physical activity and breast density across the studies by grouping them first by the timing of physical activity assessment (in adolescence, current/recent, past, and lifetime) and then by women's menopausal status (premenopausal and postmenopausal). Given the strength of the relationship between physical activity and breast cancer and the null findings of this review, it is unlikely that the effect of physical activity is mediated through an effect on breast density.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.