Evidence map›Paper›PMID 22814466›Full record

ArticleJournal of clinical microbiology2012

A longitudinal 6-year study of the molecular epidemiology of clinical campylobacter isolates in Oxfordshire, United kingdom.

Alison J Cody, Noel M McCarthy, Helen L Wimalarathna, Frances M Colles, Lorraine Clark, Ian C J W Bowler, Martin C J Maiden, Kate E Dingle

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Antimicrobial Susceptibility ofVeterinary sciences · 2025
    Article
  2. Enhanced laboratory surveillance study ofJournal of medical microbiology · 2025
    Article
  3. Applied and environmental microbiology · 2025
    Article
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  9. Article
  10. Whole-genome-based characterization ofMicrobial genomics · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Genomic Screening of Antimicrobial Resistance Markers in UK and USAntimicrobial agents and chemotherapy · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Genomic Characterisation ofFrontiers in microbiology · 2021
    Article
  20. Whole Resistome Analysis inFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alison J CodyDepartment of Zoology, University of Oxford, Oxford, UK. alison.cody@zoo.ox.ac.uk
Noel M McCarthy
Helen L Wimalarathna
Frances M Colles
Lorraine Clark
Ian C J W Bowler
Martin C J Maiden
Kate E Dingle

Funding

Wellcome Trust 087622Wellcome Trust 087622/Z/08/Z
6 · The paper itself

Abstract

Temporal and seasonal trends in Campylobacter genotypes causing human gastroenteritis were investigated in a 6-year study of 3,300 recent isolates from Oxfordshire, United Kingdom. Genotypes (sequence types [ST]) were defined using multilocus sequence typing and assigned to a clonal complex (a cluster of related strains that share four or more identical alleles with a previously defined central genotype). A previously undescribed clonal complex (ST-464) was identified which, together with ST-42, ST-45, and ST-52 complexes, showed increasing incidence. Concurrently, the incidence of ST-574, ST-607, and ST-658 complexes declined. The relative frequencies of three clonal complexes (ST-45, ST-283, and ST-42) peaked during summer and those of two (ST-353 and ST-403) peaked during winter. Nine clonal complexes (ST-22, ST-45, ST-48, ST-61, ST-257, ST-283, ST-403, ST-658, and ST-677) were significantly associated with ciprofloxacin sensitivity (P < 0.05). Seven clonal complexes (ST-49, ST-206, ST-354, ST-446, ST-460, ST-464, and ST-607) were associated with ciprofloxacin resistance (P < 0.05). Clonal complexes exhibited changing incidence and differences in seasonality and antibiotic resistance phenotype. These data also demonstrated that detailed surveillance at a single site captures information which reflects that observed nationally.

Indexed as

Multilocus Sequence TypingAdolescentAdultAgedAged, 80 and overCampylobacterCampylobacter InfectionsChildChild, PreschoolCluster AnalysisFemaleGastroenteritisGenotypeHumansInfantInfant, Newborn

Identifiers

PMID22814466
PMCPMC3457434

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.