Evidence map›Paper›PMID 22814432›Full record

ReviewVirus research2013

Cellular RNA helicases and HIV-1: insights from genome-wide, proteomic, and molecular studies.

Chia-Yen Chen, Xiang Liu, Kathleen Boris-Lawrie, Amit Sharma, Kuan-Teh Jeang

Abstract readReview
In one paragraph

Review in Virus research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Unveiling the DHX15-G-patch interplay in retroviral RNA packaging.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chia-Yen ChenMolecular Virology Section 1, Laboratory of Molecular, Microbiology, The National Institute of Allergy and Infectious Diseases, The National Institutes of Health, Bethesda, MD 20892, USA.
Xiang Liu
Kathleen Boris-Lawrie
Amit Sharma
Kuan-Teh Jeang
National Institutes of Health · USThe Ohio State University · USNational Institute of Allergy and Infectious Diseases · US

Funding

Role of Inflammation in Tax-mediated TumorigenesisP01CA100730 · NCI · WASHINGTON UNIVERSITY · PI Malachi Griffith · 2003 to 2026
$44.8M
Molecular Mechanisms Of Human Immunodeficiency Virus Trans-regulatory ProteinsZIAAI000547 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI JEANG, KUAN-TEH · 2009 to 2013
$5.9M
MOLECULAR MECHANISMS OF HUMAN RETROVIRUS TRANS-REGULATORY PROTEINSZ01AI000547 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI JEANG, KUAN-TEH · 1989 to 2008
$2.8M
Translational Control of Retroviral Unspliced mRNAR01CA108882 · NCI · OHIO STATE UNIVERSITY · PI BORIS-LAWRIE, KATHLEEN A. · 2006 to 2010
$976k
CAP: Circulating microRNAs as a Diagnostic Platform for Hepatitis C PathogenesisZIAAI001162 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI JEANG, KUAN-TEH · 2012 to 2012
$41k
Intramural NIH HHS Z01 AI000547Intramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI001162NCI NIH HHS P01 CA100730NCI NIH HHS P30CA100730NCI NIH HHS R01 CA108882NCI NIH HHS R01CA108882NIAID NIH HHS Y99 AI999999
6 · The paper itself

Abstract

RNA helicases are ubiquitous in plants and animals and function in many cellular processes. Retroviruses, such as human immunodeficiency virus (HIV-1), encode no RNA helicases in their genomes and utilize host cellular RNA helicases at various stages of their life cycle. Here, we briefly summarize the roles RNA helicases play in HIV-1 replication that have been identified recently, in part, through genome-wide screenings, proteomics, and molecular studies. Some of these helicases augment virus propagation while others apparently participate in antiviral defenses against viral replication.

Indexed as

AnimalsGene Expression Regulation, ViralGenomeHIV-1HIV InfectionsHumansProteomicsRNA HelicasesVirus ReplicationRNA Helicases

Identifiers

PMID22814432
PMCPMC3493675
OpenAlexW2076021468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.