Evidence map›Paper›PMID 22814173›Full record

SynthesisEnvironmental health perspectives2012

Concentration-response function for ozone and daily mortality: results from five urban and five rural U.K. populations.

Richard W Atkinson, Dahai Yu, Ben G Armstrong, Sam Pattenden, Paul Wilkinson, Ruth M Doherty, Mathew R Heal, H Ross Anderson

Abstract readMeta-Analysis
In one paragraph

Synthesis in Environmental health perspectives, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. An assessment of OFrontiers in public health · 2023
    Article
  3. Identification of Health Effects of Complex Air Pollution in China.International journal of environmental research and public health · 2022
    Article
  4. Concentration-Response Functions as an Essence of the Results from Lags.International journal of environmental research and public health · 2022
    Article
  5. Review
  6. Article
  7. Climate change impacts on human health over Europe through its effect on air quality.Environmental health : a global access science source · 2017
    Review
  8. Article
  9. Article
  10. Tempo-Spatial Variations of Ambient Ozone-Mortality Associations in the USA: Results from the NMMAPS Data.International journal of environmental research and public health · 2016
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard W AtkinsonDivision of Population Health Sciences and Education and MRC-HPA Centre for Environment and Health, St George's, University of London, London, United Kingdom. atkinson@sgul. ac.uk
Dahai Yu
Ben G Armstrong
Sam Pattenden
Paul Wilkinson
Ruth M Doherty
Mathew R Heal
H Ross Anderson

Funding

Department of Health
6 · The paper itself

Abstract

backgroundShort-term exposure to ozone has been associated with increased daily mortality. The shape of the concentration-response relationship-and, in particular, if there is a threshold-is critical for estimating public health impacts.

objectiveWe investigated the concentration-response relationship between daily ozone and mortality in five urban and five rural areas in the United Kingdom from 1993 to 2006.

methodsWe used Poisson regression, controlling for seasonality, temperature, and influenza, to investigate associations between daily maximum 8-hr ozone and daily all-cause mortality, assuming linear, linear-threshold, and spline models for all-year and season-specific periods. We examined sensitivity to adjustment for particles (urban areas only) and alternative temperature metrics.

resultsIn all-year analyses, we found clear evidence for a threshold in the concentration-response relationship between ozone and all-cause mortality in London at 65 µg/m3 [95% confidence interval (CI): 58, 83] but little evidence of a threshold in other urban or rural areas. Combined linear effect estimates for all-cause mortality were comparable for urban and rural areas: 0.48% (95% CI: 0.35, 0.60) and 0.58% (95% CI: 0.36, 0.81) per 10-µg/m3 increase in ozone concentrations, respectively. Seasonal analyses suggested thresholds in both urban and rural areas for effects of ozone during summer months.

conclusionsOur results suggest that health impacts should be estimated across the whole ambient range of ozone using both threshold and nonthreshold models, and models stratified by season. Evidence of a threshold effect in London but not in other study areas requires further investigation. The public health impacts of exposure to ozone in rural areas should not be overlooked.

Indexed as

Environmental ExposureMortalityAir PollutantsDose-Response Relationship, DrugEnvironmental MonitoringHumansModels, TheoreticalOzoneParticle SizeParticulate MatterPoisson DistributionRegression AnalysisRural PopulationSeasonsTemperatureTime FactorsAir PollutantsOzoneParticulate Matter

Identifiers

PMID22814173
PMCPMC3491921

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.