ArticleGenome biology and evolution2012
Evidence of a paucity of genes that interact with the mitochondrion on the X in mammals.
Article in Genome biology and evolution, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 40 citations in OpenAlex.
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- High heterogeneity in genomic differentiation between phenotypically divergent songbirds: a test of mitonuclear co-introgression.Heredity · 2023Article
- Widespread genomic signatures of reproductive isolation and sex-specific selection in the Eastern Yellow Robin, Eopsaltria australis.G3 (Bethesda, Md.) · 2022Article
- Migration restores hybrid incompatibility driven by mitochondrial-nuclear sexual conflict.Proceedings. Biological sciences · 2022Article
- Gene-Level, but Not Chromosome-Wide, Divergence between a Very Young House Fly Proto-Y Chromosome and Its Homologous Proto-X Chromosome.Molecular biology and evolution · 2021Article
- The Aphid X Chromosome Is a Dangerous Place for Functionally Important Genes: Diverse Evolution of Hemipteran Genomes Based on Chromosome-Level Assemblies.Molecular biology and evolution · 2020Article
- Cytonuclear Genetic Incompatibilities in Plant Speciation.Plants (Basel, Switzerland) · 2020Review
- Sexual conflict through mother's curse and father's curse.Theoretical population biology · 2019Article
- Temperature-Sensitive Reproduction and the Physiological and Evolutionary Potential for Mother's Curse.Integrative and comparative biology · 2019Article
- Mitochondrial genetic effects on reproductive success: signatures of positive intrasexual, but negative intersexual pleiotropy.Proceedings. Biological sciences · 2018Article
- The Mitonuclear Dimension of Neanderthal and Denisovan Ancestry in Modern Human Genomes.Genome biology and evolution · 2017Article
- Integrative Approaches for Studying Mitochondrial and Nuclear Genome Co-evolution in Oxidative Phosphorylation.Frontiers in genetics · 2017Article
- Mitochondrial-Nuclear Interactions Mediate Sex-Specific Transcriptional Profiles in Drosophila.Genetics · 2016Article
- Mitonuclear linkage disequilibrium in human populations.Proceedings. Biological sciences · 2015Article
- Mitonuclear Ecology.Molecular biology and evolution · 2015Review
- Deficit of mitonuclear genes on the human X chromosome predates sex chromosome formation.Genome biology and evolution · 2015Article
- Chromosomal distribution of cytonuclear genes in a dioecious plant with sex chromosomes.Genome biology and evolution · 2014Article
- Mito-nuclear interactions as drivers of gene movement on and off the X-chromosome.BMC genomics · 2014Article
- The potential role of sexual conflict and sexual selection in shaping the genomic distribution of Mito-nuclear genes.Genome biology and evolution · 2014Article
- Sex linkage of nuclear-encoded mitochondrial genes.Heredity · 2014Article
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3 authors at 1 institution in 1 country.
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Abstract
Mitochondria are essential organelles whose replication, development, and physiology are dependent upon coordinated gene interactions with both the mitochondrial and the nuclear genomes. The evolution of coadapted (CA) nuclear-mitochondrial gene combinations would be facilitated if such nuclear genes were located on the X-chromosome instead of on the autosomes because of the increased probability of cotransmission. Here, we test the prediction of the CA hypothesis by investigating the chromosomal distribution of nuclear genes that interact with mitochondria. Using the online genome database BIOMART, we compared the density of genes that have a mitochondrion cellular component annotation across chromosomes in 16 vertebrates. We find a strong and highly significant genomic pattern against the CA hypothesis: nuclear genes interacting with the mitochondrion are significantly underrepresented on the X-chromosome in mammals but not in birds. We interpret our findings in terms of sexual conflict as a mechanism that may generate the observed pattern. Our finding extends single-gene theory for the evolution of sexually antagonistic genes to nuclear-mitochondrial gene combinations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.