Trial reportNeuropsychologia2013
Time, action and psychosis: using subjective time to investigate the effects of ketamine on sense of agency.
Trial report in Neuropsychologia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Brain Networks, Neurotransmitters and Psychedelics: Towards a Neurochemistry of Self-Awareness.Current neurology and neuroscience reports · 2024Review
- Increased temporal binding during voluntary motor task under local anesthesia.Scientific reports · 2023Article
- Mechanisms of ketamine and its metabolites as antidepressants.Biochemical pharmacology · 2022Review
- Interrupted Time Experience in Autism Spectrum Disorder: Empirical Evidence from Content Analysis.Journal of autism and developmental disorders · 2019Article
- Article
- Voluntary action and tactile sensory feedback in the intentional binding effect.Experimental brain research · 2016Article
- Ketamine: stimulating antidepressant treatment?BJPsych open · 2016Article
- Chronic administration of ketamine mimics the perturbed sense of body ownership associated with schizophrenia.Psychopharmacology · 2015Article
- Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Article
- Sub-anesthetic ketamine modulates intrinsic BOLD connectivity within the hippocampal-prefrontal circuit in the rat.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Article
- Connectivity, pharmacology, and computation: toward a mechanistic understanding of neural system dysfunction in schizophrenia.Frontiers in psychiatry · 2013Article
- Activating memories of depression alters the experience of voluntary action.Experimental brain research · 2013Article
- Impaired Representation of Time in Schizophrenia Is Linked to Positive Symptoms and Cognitive Demand.PloS one · 2013Article
- The coherent organization of mental life depends on mechanisms for context-sensitive gain-control that are impaired in schizophrenia.Frontiers in psychology · 2013Article
- Egocentric spatial learning in schizophrenia investigated with functional magnetic resonance imaging.NeuroImage. Clinical · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Sense of agency refers to the experience of initiating and controlling actions in order to influence events in the outside world. A disturbed sense of agency is found in certain psychiatric and neurological disorders, most notably schizophrenia. Sense of agency is associated with a subjective compression of time: actions and their outcomes are perceived as bound together in time. This is known as 'intentional binding' and, in healthy adults, depends partly on advance prediction of action outcomes. Notably, this predictive contribution is disrupted in patients with schizophrenia. In the present study we aimed to characterise the psychotomimetic effect of ketamine, a drug model for psychosis, on the predictive contribution to intentional binding. It was shown that ketamine produced a disruption that closely resembled previous data from patients in the early, prodromal, stage of schizophrenic illness. These results are discussed in terms of established models of delusion formation in schizophrenia. The link between time and agency, more generally, is also considered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.