Evidence map›Paper›PMID 22811949›Full record

ArticleInternational journal of evolutionary biology2012

Novel genes from formation to function.

Rita Ponce, Lene Martinsen, Luís M Vicente, Daniel L Hartl

Open access · hybridAbstract read
In one paragraph

Article in International journal of evolutionary biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Rita PonceCentro de Biologia Ambiental (CBA), Faculdade de Ciências da Universidade de Lisboa, 1749 Lisboa, Portugal.
Lene Martinsen
Luís M Vicente
Daniel L Hartl
Harvard University · USUniversity of Lisbon · PT

Funding

Evolution of Genome IncompatibilitiesR01GM065169 · NIGMS · HARVARD UNIVERSITY · PI HARTL, DANIEL L · 2003 to 2011
$2.5M
Novel genomic effects of Y-linked polymorphismsR01GM084236 · NIGMS · HARVARD UNIVERSITY · PI HARTL, DANIEL L · 2009 to 2012
$1.2M
NIGMS NIH HHS R01 GM065169NIGMS NIH HHS R01 GM084236
6 · The paper itself

Abstract

The study of the evolution of novel genes generally focuses on the formation of new coding sequences. However, equally important in the evolution of novel functional genes are the formation of regulatory regions that allow the expression of the genes and the effects of the new genes in the organism as well. Herein, we discuss the current knowledge on the evolution of novel functional genes, and we examine in more detail the youngest genes discovered. We examine the existing data on a very recent and rapidly evolving cluster of duplicated genes, the Sdic gene cluster. This cluster of genes is an excellent model for the evolution of novel genes, as it is very recent and may still be in the process of evolving.

Identifiers

PMID22811949
PMCPMC3395120
OpenAlexW2119212318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.