Evidence map›Paper›PMID 22811608›Full record

ArticleInternational journal of medical sciences2012

BioShuttle mobility in living cells studied with high-resolution FCS & CLSM methodologies.

Klaus Braun, Marcel Beining, Manfred Wiessler, Twan Lammers, Rüdiger Pipkorn, Ute Hennrich, Kiyoshi Nokihara, Wolfhard Semmler, Jürgen Debus, Waldemar Waldeck

Abstract read
In one paragraph

Article in International journal of medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. SPPS resins impact the PNA-syntheses' improvement.International journal of medical sciences · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Klaus BraunDept. of Imaging and Radiooncology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, Germany. k.braun@dkfz.de
Marcel Beining
Manfred Wiessler
Twan Lammers
Rüdiger Pipkorn
Ute Hennrich
Kiyoshi Nokihara
Wolfhard Semmler
Jürgen Debus
Waldemar Waldeck

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increase in molecular diagnostics and patient-specific therapeutic approaches, the delivery and targeting of imaging molecules and pharmacologically active agents gain increasing importance. The ideal delivery system does not exist yet. The realization of two features is indispensable: first, a locally high concentration of target-specific diagnostic and therapeutic molecules; second, the broad development of effective and safe carrier systems. Here we characterize the transport properties of the peptide-based BioShuttle transporter using FFM and CLSM methods. The modular design of BioShuttle-based formulations results in a multi-faceted field of applications, also as a theranostic tool.

Indexed as

Cell Line, TumorHeLa CellsHumansMicroscopy, ConfocalMicroscopy, FluorescenceMolecular ImagingBioShuttleConfocal Laser Scanning Microscopy-CLSMDrug DeliveryFluorescence Correlation Spectroscopy-FCSFluorescence Fluctuation Microscopy-FFMLigation chemistryNon-Viral Carrier SystemsSpinning Disc Microscopy-SDM.

Identifiers

PMID22811608
PMCPMC3399214

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.