ArticleEuropean journal of clinical pharmacology2013
The use of medication against attention deficit/hyperactivity disorder in Denmark: a drug use study from a patient perspective.
Article in European journal of clinical pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Use of Attention Deficit Hyperactivity Disorder Medication Among Danish Children and Adolescents From 2010 to 2023.Acta psychiatrica Scandinavica · 2026Article
- Perception of ADHD and Compliance in Relation to ADHD Medication.Acta psychiatrica Scandinavica · 2026Article
- Dose titration of osmotic release oral system methylphenidate in children and adolescents with attention-deficit hyperactivity disorder: a retrospective cohort study.BMC pediatrics · 2023Article
- Combined Medication with Stimulants and Non-stimulants for Attention-deficit/hyperactivity Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2021Article
- Methylphenidate for attention-deficit/hyperactivity disorder in adults: a narrative review.Psychopharmacology · 2021Review
- Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD.The American journal of psychiatry · 2021Article
- The definition and measurement of heterogeneity.Translational psychiatry · 2020Review
- Use of Psychotropic Drugs among Children and Adolescents with Autism Spectrum Disorders in Denmark: A Nationwide Drug Utilization Study.Journal of clinical medicine · 2018Article
- Blood pressure in children with attention deficit/hyperactivity disorder.Paediatrics & child health · 2018Article
- Use of attention-deficit/hyperactivity disorder medication among older adults in Denmark.British journal of clinical pharmacology · 2018Article
- Patterns and profiles of methylphenidate use both in children and adults.British journal of clinical pharmacology · 2018Observational
- Estimated prevalence and incidence of diagnosed ADHD and health care utilization in adults in Sweden - a longitudinal population-based register study.Neuropsychiatric disease and treatment · 2018Article
- Overuse of methylphenidate: an analysis of Swedish pharmacy dispensing data.Clinical epidemiology · 2018Article
- Factors that Affect the Adherence to ADHD Medications during a Treatment Continuation Period in Children and Adolescents: A Nationwide Retrospective Cohort Study Using Korean Health Insurance Data from 2007 to 2011.Psychiatry investigation · 2017Article
- Differences in Utilization Patterns among Medications in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: a 36-Month Retrospective Study Using the Korean Health Insurance Review and Assessment Claims Database.Journal of Korean medical science · 2016Article
- Initiation and Persistence of Pharmacotherapy for Youths with Attention Deficit Hyperactivity Disorder in Taiwan.PloS one · 2016Article
- Prescribing patterns for attention deficit hyperactivity disorder medications among children and adolescents in Korea, 2007-2011.Epidemiology and health · 2016Article
- Factors affecting treatment adherence to atomoxetine in ADHD: a systematic review.Neuropsychiatric disease and treatment · 2016Review
- Off-label prescribing of psychotropic drugs in a Danish child and adolescent psychiatric outpatient clinic.European child & adolescent psychiatry · 2016Article
- Article
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Authors and funding
6 authors.
Funding
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Abstract
aimOur aim was to characterize utilization patterns for drugs used to treat attention deficit/hyperactivity disorder (ADHD) on the level of the individual patient among Danish users, focusing on treatment duration, doses used, and concurrent use of ADHD and non-ADHD drugs.
methodsUsing the Danish Registry of Medicinal Product Statistics, we extracted data on 1,085,099 prescriptions for ADHD drugs issued to a total of 54,024 persons in the study period 1 January 1995 to 30 September 2011. For users in the final year of the study period, we further extracted 315,365 prescriptions for non-ADHD drugs. Drug utilization was characterized using descriptive statistics.
resultsThe mean duration of ADHD treatment was highest (3.6-4.2 years) for patients initiating therapy at a young age (age<13). Dropout rate after receiving only one prescription was highest among off-label users (age<6 and age >17). All age categories showed an increase in the average daily dosage of methylphenidate used from 2003 to 2010. Concomitant treatment with methylphenidate and atomoxetine was rare, as only 2 % of methylphenidate treatment overlapped with atomoxetine treatment. Nineteen percent of methylphenidate instant-release treatment overlapped with methylphenidate controlled-release treatment. Users of ADHD drugs across all age categories had an increased use of drugs related to the nervous system, especially antipsychotics [standardized morbidity rate (SMR), 6.4-19.5] and antiepileptics (SMR, 4.0-5.5).
conclusionWe found certain traits that warrant further investigation: the apparent increase in average daily doses, the low adherence to treatment among off-label users, and the increased use of other psychotropic medication.
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