Evidence map›Paper›PMID 22811254›Full record

ReviewWiley interdisciplinary reviews. Systems biology and medicine

Systems biology of skeletal muscle: fiber type as an organizing principle.

Sarah M Greising, Heather M Gransee, Carlos B Mantilla, Gary C Sieck

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Systems biology and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Respiratory Movements at Different Ages.Medicina (Kaunas, Lithuania) · 2023
    Article
  8. Review
  9. Identification of Subproteomic Markers for Skeletal Muscle Profiling.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah M GreisingDepartment of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Heather M Gransee
Carlos B Mantilla
Gary C Sieck

Funding

Recovery of Respiratory Function After Spinal Cord InjuryR01HL096750 · NHLBI · MAYO CLINIC ROCHESTER · PI MANTILLA, CARLOS B, SIECK, GARY C. · 2010 to 2017
$4.9M
Interdisciplinary Training in Lung Physiology and Biomedical EngineeringT32HL105355 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S., SIECK, GARY C. · 2012 to 2021
$3.9M
PLASTICITY IN DIAPHRAGM NEUROMOTOR CONTROLR01HL037680 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SIECK, GARY C. · 1987 to 2007
$2.6M
Influence of Innervation on Diaphragm Muscle GrowthR01AR051173 · NIAMS · MAYO CLINIC ROCHESTER · PI SIECK, GARY C. · 2004 to 2009
$2.0M
RESPIRATORY MUSCLES DURING DEVELOPMENTR01HL034817 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SIECK, GARY C. · 1986 to 2001
$518k
Influence of Innervation on Diaphragm Muscle GrowthR56AR051173 · NIAMS · MAYO CLINIC ROCHESTER · PI SIECK, GARY C. · 2010 to 2010
$355k
NHLBI NIH HHS R01 HL034817NHLBI NIH HHS R01 HL037680NHLBI NIH HHS R01 HL096750NHLBI NIH HHS T32 HL105355NIAMS NIH HHS R01 AR051173NIAMS NIH HHS R56 AR051173
6 · The paper itself

Abstract

Skeletal muscle force generation and contraction are fundamental to countless aspects of human life. The complexity of skeletal muscle physiology is simplified by fiber type classification where differences are observed from neuromuscular transmission to release of intracellular Ca(2+) from the sarcoplasmic reticulum and the resulting recruitment and cycling of cross-bridges. This review uses fiber type classification as an organizing and simplifying principle to explore the complex interactions between the major proteins involved in muscle force generation and contraction.

Indexed as

Systems BiologyAnimalsCalciumHumansMuscle ContractionMuscle ProteinsMuscle, SkeletalSarcoplasmic ReticulumCalciumMuscle Proteins

Identifiers

PMID22811254
PMCPMC3874884

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.